In vivo demonstration of noninvasive thermal surgery of the liver and kidney using an ultrasonic phased array

被引：105
作者：
Daum, DR
Smith, NB
King, R
Hynynen, K
机构：
[1] Brigham & Womens Hosp, Dept Radiol, Boston, MA 02115 USA
[2] MIT, Harvard Mit Div Hlth Sci & Technol, Cambridge, MA 02139 USA
来源：
ULTRASOUND IN MEDICINE AND BIOLOGY | 1999年 / 25卷 / 07期
关键词：
phased array; focused ultrasound; liver ablation; kidney ablation; noninvasive surgery; MR guidance; FUS; HIFU;
D O I：
10.1016/S0301-5629(99)00053-8
中图分类号：
O42 [声学];
学科分类号：
070206 ; 082403 ;
摘要：
A 256-element, continuous-wave ultrasonic phased array has been used to thermally coagulate deep-seated liver and kidney tissue. The array elements were formed on a 1-3 piezocomposite bowl with a 10-cm radius of curvature and 12-cm diameter. The 0.65 x 0.65 cm(2) projection elements were driven at 1.1 MHz by a custom-built amplifier system. A series of in vivo porcine experiments demonstrated the ability to coagulate liver and kidney tissue using the large-scale phased array. The temperature response of the treatment was guided and monitored using magnetic resonance (MR) images, Focal lesion volumes greater than 0.5 cm(3) in kidney and 2 cm(3) in liver were formed from a single 20-s sonication, (C) 1999 World Federation for Ultrasound in Medicine & Biology.
引用
收藏
页码：1087 / 1098
页数：12
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