Artificial scotoma estimation based on population receptive field mapping

被引：13

作者：

Hummer, A. ^{[1
]}

Ritter, M. ^{[2
]}

Woletz, M. ^{[1
]}

Ledolter, A. A. ^{[2
]}

Tik, M. ^{[1
]}

Dumoulin, S. O. ^{[3
]}

Holder, G. E. ^{[4
,5
,6
]}

Schmidt-Erfurth, U. ^{[2
]}

Windischberger, C. ^{[1
]}

机构：

[1] Med Univ Vienna, Ctr Med Phys & Biomed Engn, MR Ctr Excellence, Wahringer Gurtel 18-20, A-1090 Vienna, Austria

[2] Med Univ Vienna, Dept Ophthalmol & Optometry, Wahringer Gurtel 18-20, A-1090 Vienna, Austria

[3] Royal Netherlands Acad Sci, Spinoza Ctr Neuroimaging, Meibergdreef 75, Amsterdam, Netherlands

[4] Natl Univ Singapore, Dept Ophthalmol, 1E Kent Ridge Rd, Singapore 119228, Singapore

[5] Natl Univ Singapore Hosp, 1E Kent Ridge Rd, Singapore 119228, Singapore

[6] UCL, Inst Ophthalmol, 11-43 Bath St, London EC1V 9EL, England

来源：

NEUROIMAGE | 2018年 / 169卷

关键词：

HUMAN VISUAL-CORTEX; MACULAR DEGENERATION; FILLING-IN; FMRI; PROJECTION; HUMANS;

D O I：

10.1016/j.neuroimage.2017.12.010

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Population receptive field (pRF) mapping based on functional magnetic resonance imaging (fMRI) is an ideal method for obtaining detailed retinotopic information. One particularly promising application of pRF mapping is the estimation and quantification of visual field effects, for example scotomata in patients suffering from macular dysfunction or degeneration (MD) or hemianopic defects in patients with intracranial dysfunction. However, pRF mapping performance is influenced by a number of factors including spatial and temporal resolution, distribution of dural venous sinuses and patient performance. This study addresses the ability of current pRF methodology to assess the size of simulated scotomata in healthy individuals. The data demonstrate that central scotomata down to a radius of 2.35 degrees (4.7 degrees diameter) visual angle can be reliably estimated in single subjects using high spatial resolution protocols and multi-channel receive array coils.

引用

页码：342 / 351

页数：10

共 31 条

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