The Role of Lymphadenectomy in Esophageal Cancer

被引：41
作者：
Darling, Gail [1 ]
机构：
[1] Univ Toronto, Toronto Gen Hosp, Toronto, ON M5G 2C4, Canada
来源：
JOURNAL OF SURGICAL ONCOLOGY | 2009年 / 99卷 / 04期
关键词：
esophageal cancer; lymph nodes; staging; survival; SQUAMOUS-CELL CARCINOMA; EN-BLOC-ESOPHAGECTOMY; LYMPH-NODES; PROGNOSTIC-FACTORS; GASTROESOPHAGEAL JUNCTION; TRANSHIATAL ESOPHAGECTOMY; ESOPHAGOGASTRIC JUNCTION; THORACIC ESOPHAGUS; ADENOCARCINOMA; SURVIVAL;
D O I：
10.1002/jso.21209
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Lymph node metastases are common in esophageal cancer and are associated with a poor prognosis. Resection and examination of 15-18 lymph nodes is required for adequate staging of esophageal cancer. Improved Survival is associated with involvement of five or fewer nodes or lymph node ratio (LNR) of <0.10-0.20. More extensive lymph node dissection during esophagectomy offers improved staging but may also provide therapeutic benefit in terms of control of locoregional disease and possibly improved overall survival. J Surg. Oncol. 2009;99:189-193. (C) 2008 Wiley-Liss, Inc.
引用
收藏
页码：189 / 193
页数：5
相关论文
共 30 条
  • [1] RADICAL LYMPH-NODE DISSECTION FOR CANCER OF THE THORACIC ESOPHAGUS
    AKIYAMA, H
    TSURUMARU, M
    UDAGAWA, H
    KAJIYAMA, Y
    [J]. ANNALS OF SURGERY, 1994, 220 (03) : 364 - 373
  • [2] En bloc esophagectomy improves survival for stage III esophageal cancer
    Altorki, NK
    Girardi, L
    Skinner, DB
    [J]. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1997, 114 (06) : 948 - 955
  • [3] QUALITY OF LIFE AND PATTERNS OF RECURRENCE FOLLOWING TRANSHIATAL ESOPHAGECTOMY FOR CANCER - RESULTS OF A PROSPECTIVE FOLLOW-UP IN 50 PATIENTS
    BARBIER, PA
    LUDER, PJ
    SCHUPFER, G
    BECKER, CD
    WAGNER, HE
    [J]. WORLD JOURNAL OF SURGERY, 1988, 12 (02) : 270 - 275
  • [4] Lymphadenectomy for adenocarcinoma of the gastroesophageal junction (GEJ): Impact of adequate staging on outcome
    Barbour, Andrew P.
    Rizk, Nabil P.
    Gonen, Mithat
    Tang, Laura
    Bains, Manjit S.
    Rusch, Valerie W.
    Coit, Daniel G.
    Brennan, Murray F.
    [J]. ANNALS OF SURGICAL ONCOLOGY, 2007, 14 (02) : 306 - 316
  • [5] Staging of esophageal carcinoma:: Length of tumor and number of involved regional lymph nodes.: Are these independent prognostic factors?
    Bollschweiler, Elfriede
    Baldus, Stephan E.
    Schroeder, Wolfgang
    Schneider, Paul M.
    Hoelscher, Arnulf H.
    [J]. JOURNAL OF SURGICAL ONCOLOGY, 2006, 94 (05) : 355 - 363
  • [6] Dutkowski P, 2002, HEPATO-GASTROENTEROL, V49, P176
  • [7] ESOPHAGEAL SQUAMOUS-CELL CARCINOMA .1. A CRITICAL-REVIEW OF SURGERY
    EARLAM, R
    CUNHAMELO, JR
    [J]. BRITISH JOURNAL OF SURGERY, 1980, 67 (06) : 381 - 390
  • [8] Prognostic factors for the survival of patients with esophageal carcinoma in the US - The importance of tumor length and lymph node status
    Eloubeidi, MA
    Desmond, R
    Arguedas, MR
    Reed, CE
    Wilcox, CM
    [J]. CANCER, 2002, 95 (07) : 1434 - 1443
  • [9] FUMAGALLI U, 1996, DIS ESOPHGUS, V9, pS30
  • [10] Prognostic significance of the number of lymph node metastases in esophageal cancer
    Greenstein, Alexander J.
    Litle, Virginia R.
    Swanson, Scott J.
    Divino, Celia M.
    Packer, Stuart
    Wisnivesky, Juan P.
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2008, 206 (02) : 239 - 246
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