Gene family matters: expanding the HGNC resource

被引：11

作者：

Daugherty, Louise C. ^{[1
]}

Seal, Ruth L. ^{[1
]}

Wright, Mathew W. ^{[1
]}

Bruford, Elspeth A. ^{[1
]}

机构：

[1] European Bioinformat Inst EMBL EBI, Hinxton CB10 1SD, Cambs, England

来源：

HUMAN GENOMICS | 2012年 / 6卷

基金：

英国惠康基金;

关键词：

GENOME DATABASE; NOMENCLATURE; MOUSE;

D O I：

10.1186/1479-7364-6-4

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The HUGO Gene Nomenclature Committee (HGNC) assigns approved gene symbols to human loci. There are currently over 33,000 approved gene symbols, the majority of which represent protein-coding genes, but we also name other locus types such as non-coding RNAs, pseudogenes and phenotypic loci. Where relevant, the HGNC organise these genes into gene families and groups. The HGNC website http://www.genenames.org/ is an online repository of HGNC-approved gene nomenclature and associated resources for human genes, and includes links to genomic, proteomic and phenotypic information. In addition to this, we also have dedicated gene family web pages and are currently expanding and generating more of these pages using data curated by the HGNC and from information derived from external resources that focus on particular gene families. Here, we review our current online resources with a particular focus on our gene family data, using it to highlight our new Gene Symbol Report and gene family data downloads.

引用

页数：6

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