Analytical model of graphene-based biosensors for bacteria detection

被引:5
作者
Akbari, Elnaz [1 ]
Buntat, Zolkafle [1 ]
Kiani, Mohammad J. [2 ,3 ]
Enzevaee, Aria [4 ]
Khaledian, Mohsen [3 ]
机构
[1] Univ Teknol Malaysia, Inst High Voltage & High Current, Fac Elect Engn, Johor Baharu 81310, Malaysia
[2] Hakim Sabzevari Univ, Fac Elect & Comp Engn, Sabzevar 9617976487, Iran
[3] Univ Teknol Malaysia, Fac Elect Engn, Skudai 81310, Johor, Malaysia
[4] Univ Teknol Malaysia, Fac Mech Engn, Johor Baharu 81310, Malaysia
关键词
I-V characteristics; E. coli bacteria; field effect transistor; graphene; biosensor; CARBON NANOTUBES;
D O I
10.1080/03067319.2015.1058930
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
In this research, a set of novel models based on field effect transistor (FET) structure using graphene have been proposed with the current-voltage (I-V) characteristics of graphene employed to model the sensing mechanism. It has been observed that the graphene device experiences a drastic increase in conductance when exposed to Escherichia coli bacteria at 0- [GRAPHICS] cfu/mL concentrations. Hence, simplicity of the structure, fast response rate and high sensitivity of this nanoelectronic biosensor make it a more suitable device in screening and functional studies of antibacterial drugs and an ideal high-throughput platform that can detect any pathogenic bacteria. Accordingly, the proposed model exhibits a satisfactory agreement with the experimental data.
引用
收藏
页码:847 / 854
页数:8
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