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Lichenysin-geminal amino acid-based surfactants: Synergistic action of an unconventional antimicrobial mixture
被引:12
|作者:
Coronel-Leon, Jonathan
[1
,3
]
Pinazo, Aurora
[2
]
Perez, Lourdes
[2
]
Jose Espuny, Ma
[1
]
Ma Marques, Ana
[1
]
Manresa, Angeles
[1
]
机构:
[1] Univ Barcelona, Fac Farm, Microbiol Lab, Joan XXIII S-N, E-08028 Barcelona, Spain
[2] IQAC CSIC, Dept Chem & Surfactant Technol, Jordi Girona 18-26, Barcelona 08034, Spain
[3] Escuela Super Politecn Litoral, ESPOL, Fac Ingn Mecan & Ciencias Prod, Campus Gustavo Galindo Km 30-5 Via Perimetral, Guayaquil, Ecuador
关键词:
Antimicrobial properties;
Lichenysin;
Flow cytometry;
Transmission electron microscopy;
Potassium leakage;
Gemini surfactants;
Arginine;
Listeria nonocytogenes;
Escherichia coli;
CATIONIC SURFACTANTS;
PSEUDOMONAS-AERUGINOSA;
STAPHYLOCOCCUS-AUREUS;
ARGININE;
AGGREGATION;
RHAMNOLIPIDS;
PEPTIDE;
WATER;
D O I:
10.1016/j.colsurfb.2016.10.008
中图分类号:
Q6 [生物物理学];
学科分类号:
071011 ;
摘要:
Recently it has been demonstrated that catanionic mixtures of oppositely charged surfactants have improved physicochemical-biological properties compared to the individual components. Isotherms of mixtures of an anionic biosurfactant (lichenysin) and a cationic aminoacid surfactant (C-3(LA)(2)) indicate a strong interaction suggesting the formation of a new "pseudo-surfactant". The antimicrobial properties of the mixture lichenysin and C-3(LA)(2) M80:20, indicate a synergistic effect of the components. The mechanism of action on the bacterial envelope was assessed by flow cytometry and Transmission Electron Microscopy. (C) 2016 Elsevier B.V. All rights reserved.
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页码:38 / 47
页数:10
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