DNA Origami Design: A How-To Tutorial

被引：10

作者：

Majikes, Jacob M. ^{[1
]}

Liddle, J. Alexander ^{[1
,2
]}

机构：

[1] NIST, Microsyst & Nanotechnol Div, Gaithersburg, MD 20899 USA

[2] NIST, US Dept Commerce, Gaithersburg, MD 20899 USA

来源：

JOURNAL OF RESEARCH OF THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY | 2021年 / 126卷

关键词：

DNA nanofabrication; DNA origami; self-assembly; MOLECULAR-DYNAMICS; FOLDING DNA; THERMODYNAMICS; PATHWAY; SHAPES;

D O I：

10.6028/jres.126.001

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

While the design and assembly of DNA origami are straightforward, its relative novelty as a nanofabrication technique means that the tools and methods for designing new structures have not been codified as well as they have for more mature technologies, such as integrated circuits. While design approaches cannot be truly formalized until design-property relationships are fully understood, this document attempts to provide a step-by-step guide to designing DNA origami nanostructures using the tools available at the current state of the art.

引用

页数：33

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