Coagulation 2006: A modern view of hemostasis

被引：166

作者：

Hoffman, Maureane

Monroe, Dougald M.

机构：

[1] Vet Adm Med Ctr, Pathol & Lab Med Serv 113, Durham, NC 27705 USA

[2] Duke Univ, Med Ctr, Dept Pathol, Durham, NC 27710 USA

[3] Univ N Carolina, Chapel Hill, NC 27514 USA

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2007年 / 21卷 / 01期

关键词：

D O I：

10.1016/j.hoc.2006.11.004

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The authors propose that hemostasis occurs in a stepwise process, regulated by cellular components in vivo. The effectiveness of hemostasis in vivo depends not only on the procoagulant reactions but also on the fibrinolytic process. Causes of coagulopathic bleeding include consumption of coagulation factors and platelets, excessive fibrinolysis, hyothermia, and acidosis. Generation of the right amount of thrombin during the coagulation process not only may be essential for effective hemostasis but also may set the stage for effective wound healing.

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页数：12

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