Tongue-out versus tongue-in position during intensity-modulated radiotherapy for base of tongue cancer: Clinical implications for minimizing post-radiotherapy swallowing dysfunction

被引：4

作者：

Kil, Whoon Jong ^{[1
,2
]}

Kulasekere, Christina ^{[1
]}

Hatch, Craig ^{[1
]}

Bugno, Jacob ^{[1
]}

Derrwaldt, Ronald ^{[1
]}

机构：

[1] Cleveland Vet Affairs Med Ctr, Cleveland, OH USA

[2] Oklahoma City Vet Affairs Med Ctr, Med Serv, Radiat Oncol Sect, 921 NE 13th St, Oklahoma City, OK 73104 USA

来源：

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2017年 / 39卷 / 08期

关键词：

base of tongue cancer; customized immobilization mask; intensity-modulated radiotherapy (IMRT); swallowing dysfunction; tongue-out; NECK-CANCER; REDUCE DYSPHAGIA; HEAD; THERAPY; IMRT;

D O I：

10.1002/hed.24809

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Background: The purpose of this study was to assess whether different tongue positions change the radiation doses to swallowing organs at risks: the pharyngeal constrictor, oral cavity, and larynx during intensity-modulated radiotherapy (IMRT) for base of tongue (BOT) cancer. Methods: IMRT plans with Tongue-out (IMRT-TO) and tongue-in position (IMRT-TI) was compared in 3 cases. Results: Distance from BOT to pharyngeal constrictor was increased to 1.8 +/- 0.8 cm with IMRTTO from 0.9 + 0.6 cm with IMRT-TI (P < .01). Compared to IMRT-TI, IMRT-TO significantly decreased the radiation dose to the anterior oral cavity, oral tongue, superior pharyngeal constrictor, middle pharyngeal constrictor, and supraglottic larynx (all P <= .04). IMRT-TO also had a smaller volume irradiated than IMRT-TI to the anterior oral cavity and the oral tongue receiving >= 30 Gy (V30) and V35, and superior pharyngeal constrictor and middle pharyngeal constrictor for V55 and V65 (all P <= .04). Conclusion: Dosimetric advantage with IMRT-TO over IMRT-TI may potentially reduce post-IMRT swallowing dysfunction in selected patients with BOT cancer.

引用

页码：E85 / E91

页数：7

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