Reconstruction of a Rabbit Ulna Bone Defect Using Bone Marrow Stromal Cells and a PLA/β-TCP Composite by a Novel Sintering Method

被引:5
|
作者
Jung, Youngmee [1 ]
Park, Min Sung [2 ]
Kim, Sang-Soo [3 ]
Kim, Byung-Soo [3 ]
Kim, Young Ha [4 ]
Kim, Sang-Heon [1 ]
Lee, Jin Woo [2 ,5 ]
Kim, Soo Hyun [1 ]
机构
[1] Korea Adv Inst Sci & Technol, Biomat Res Ctr, Seoul 130650, South Korea
[2] Yonsei Univ, Brain Korea Project Med Sci 21, Seoul 120752, South Korea
[3] Hanyang Univ, Dept Bioengn, Seoul 133791, South Korea
[4] Gwangju Inst Sci & Technol, Dept Mat Sci & Engn, Kwangju 500712, South Korea
[5] Yonsei Univ, Dept Orthopaed Surg, Seoul 120752, South Korea
关键词
TRICALCIUM PHOSPHATE; GRAFT SUBSTITUTES; TISSUE; REGENERATION; STIMULATION; SCAFFOLD; CULTURE; REPAIR; MODEL;
D O I
10.1002/adem.200900013
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
We developed PLA/β-TCP composites with a novel sintering method in order to enhance cellular interaction with matrices for bone regeneration. Thereafter, we confirmed the superior bone-forming characteristics of PLA/β-TCP cell-composite constructs resulting from greater surface exposure of the β-TCP particles, which may yield higher osteogenic and osteoconductive properties. © 2009 WILEY-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:B169 / B176
页数:8
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