Prevalence of ocular manifestation in 198 patients with rheumatoid arthritis: a restrospective study

被引:20
作者
Bettero, Raphael Guimaraes [1 ]
Martinez Cebrian, Ricardo Faraco [1 ]
Skare, Thelma Larocca [1 ]
机构
[1] Hosp Univ Evangel Curitiba, Fac Evangel Parana, Serv Reumatol, Curitiba, Parana, Brazil
关键词
Rheumatoid arthritis/complications; Eye diseases/epidemiology; keratoconjunctivitis sicca; Sjogren's syndrome; Antibodies; antinuclear;
D O I
10.1590/S0004-27492008000300011
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To study the prevalence of eye manifestations in the local rheumatoid arthritis (RA) population, as well as to know if the presence of rheumatoid factor (RF) and antinuclear antibodies (ANA) affect this profile. To study if there is association between eye manifestations and patient's articular functional index, age at diagnosis and illness duration. Methods: We reviewed 198 charts of rheumatoid arthritis patients followed-up from 2003 to 2006. They were studied for: prevalence of ophthalmologic manifestations, autoantibody profile, demographic data and Steinbrock's functional index. Results: Secondary Sjogren's syndrome was seen in 12.1% of the patients being more common in women (p=0.049) and in patients with greater articular damage (p=0.016). Ulcerative keratitis and scleritis appeared in 2% of patients each. Antinuclear antibodies (ANA) and rheumatoid factor (RF) as well as illness duration and age at diagnosis had no influence in the appearance of eye manifestations. Conclusion: Secondary Sjogren syndrome was the most common ocular manifestation in patients with RA, mainly in women and patients with greater joint damage.
引用
收藏
页码:365 / 369
页数:5
相关论文
共 27 条
  • [1] BRON JA, 1998, RHEUMATOLOGY, V1
  • [2] Clinical significance of low titer anti-nuclear antibodies in early rheumatoid arthritis: implications on the presentation and long-term course of the disease
    Caspi, D
    Elkayam, O
    Eisinger, M
    Vardinon, N
    Yaron, M
    Burke, M
    [J]. RHEUMATOLOGY INTERNATIONAL, 2001, 20 (02) : 43 - 47
  • [3] Ciconelli R.M., 2004, GUIA REUMATOLOGIA, P85
  • [4] Peripheral ulcerative keratitis in rheumatoid arthritis: successful use of intravenous cyclophosphamide and comparison of clinical and serological characteristics
    Clewes, AR
    Dawson, JK
    Kaye, S
    Bucknall, RC
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 2005, 64 (06) : 961 - 962
  • [5] COLES RS, 1985, HOSP PRACT, V20, P70
  • [6] COLES RS, 1985, HOSP PRACT, V20, P78
  • [7] COLES RS, 1985, HOSP PRACT, V20, P80
  • [8] FACTORS PREDICTING A POOR LIFE PROGNOSIS IN RHEUMATOID-ARTHRITIS - AN 8 YEAR PROSPECTIVE-STUDY
    ERHARDT, CC
    MUMFORD, PA
    VENABLES, PJW
    MAINI, RN
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 1989, 48 (01) : 7 - 13
  • [9] FOX R, 1997, TXB RHEUMATOLOGY, V1, P955
  • [10] Fox RI, 1997, CLIN LAB MED, V17, P431