Post-COVID-19 arthritis: a case report and literature review

被引:60
作者
Gasparotto, M. [1 ]
Framba, V. [2 ,3 ]
Piovella, C. [2 ,3 ]
Doria, A. [1 ]
Iaccarino, Luca [1 ,4 ]
机构
[1] Univ Padua, Dept Med DIMED, Rheumatol Unit, Padua, Italy
[2] Univ Padua, Dept Med DIMED, Internal Med Unit, Padua, Italy
[3] Univ Padua, Dept Med DIMED, Reg Liver Dis Reference Ctr, Padua, Italy
[4] Univ Padua, Div Rheumatol, Via Giustiniani 2, I-35128 Padua, Italy
关键词
Arthritis; COVID-19; Molecular mimicry; Reactive arthritis; SARS-CoV2;
D O I
10.1007/s10067-020-05550-1
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) is the novel pathogen responsible for the coronavirus disease 19 (COVID-19) outbreak. Researchers and clinicians are exploring the pathogenetic mechanisms of the viral-induced damage and growing interest is focusing on the short-term and long-term immune-mediated consequences triggered by the infection. We will focus on post-SARS-CoV2 infection arthritis which may arise as a new pathological condition associated with COVID-19. In this article, we describe a case of acute oligoarthritis occurring 13 days after a SARS-CoV2 severe pneumonia in a middle-aged Caucasian man and we go over a brief review of the current available literature. We hypothesize that molecular mimicry might be the basic immunological mechanism responsible for the onset of COVID-19-related arthritis based on the current knowledge of SARS-CoV2 and on the known pathogenetic mechanism of viral-induced arthritis.
引用
收藏
页码:3357 / 3362
页数:6
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