Epidemiological data reveal a decline in the incidence of appendicitis and appendectomy in the industrialized countries. A peak is found in adolescents aged 10-19 years; however, the highest rates of perforation are reported for the extremely young and old age groups. The elevated rate of appendectomies without histological evidence of acute inflammation, especially in young women, and the high perforation ratio in small children and elderly patients reflect poor diagnostic accuracy. Analysis of the epidemiological data does not allow for an unequivocal conclusion regarding the etiopathogenesis of acute appendicitis.
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Global Alliance Infect Surg, Vila Nova De Gaia, PortugalGlobal Alliance Infect Surg, Vila Nova De Gaia, Portugal
Labricciosa, Francesco M.
Sartelli, Massimo
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Macerata Hosp, Dept Surg, Macerata, ItalyGlobal Alliance Infect Surg, Vila Nova De Gaia, Portugal
Sartelli, Massimo
Barbadoro, Pamela
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Univ Politecn Marche, Dept Biomed Sci & Publ Hlth, Unit Hyg Prevent Med & Publ Hlth, Ancona, ItalyGlobal Alliance Infect Surg, Vila Nova De Gaia, Portugal
Barbadoro, Pamela
Abbo, Lilian M.
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Miami Miller Sch Med, Infect Dis Univ, Miami, FL USA
Jackson Hlth Syst, Miami, FL USAGlobal Alliance Infect Surg, Vila Nova De Gaia, Portugal
Abbo, Lilian M.
Ansaloni, Luca
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Bufalini Hosp, Gen Emergency & Trauma Surg Dept, Cesena, ItalyGlobal Alliance Infect Surg, Vila Nova De Gaia, Portugal
Ansaloni, Luca
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Coccolini, Federico
Catena, Fausto
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Parma Univ Hosp, Emergency Surg Dept, Parma, ItalyGlobal Alliance Infect Surg, Vila Nova De Gaia, Portugal