Dendronized iron oxide nanoparticles as contrast agents for MRI

被引:110
作者
Basly, Brice [1 ]
Felder-Flesch, Delphine [1 ]
Perriat, Pascal [2 ]
Billotey, Claire [3 ]
Taleb, Jacqueline [3 ]
Pourroy, Genevieve [1 ]
Begin-Colin, Sylvie [1 ]
机构
[1] UMR CNRS UdS ECPM 7504, IPCMS, F-67034 Strasbourg, France
[2] CNRS INSA Lyon, UMR 5510, Etud Met Phys & Phys Mat Grp, F-69621 Villeurbanne, France
[3] Univ Lyon 1, Lab CREATIS LRMN, CNRS UMR 5220, INSA Lyon,INSERM,U630, F-69621 Villeurbanne, France
关键词
MAGNETITE-BASED NANOPARTICLES; DRUG-DELIVERY; BIOMEDICAL APPLICATIONS; COUPLING AGENT; RESONANCE; THERAPY; FUNCTIONALIZATION; STABILIZATION; DIAGNOSIS; OXIDATION;
D O I
10.1039/b920348f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Covalent attachment, through a phosphonate anchor, of hydrophilic pegylated dendrons on iron oxide nanoparticles results in versatile, robust, and highly relaxing MRI contrast agents.
引用
收藏
页码:985 / 987
页数:3
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共 41 条
  • [1] Versatile PEG-derivatized phosphine oxide ligands for water-dispersible metal oxide nanocrystals
    Bin Na, Hyon
    Lee, In Su
    Seo, Heonjin
    Park, Yong Il
    Lee, Jung Hee
    Kim, Sang-Wook
    Hyeon, Taeghwan
    [J]. CHEMICAL COMMUNICATIONS, 2007, (48) : 5167 - 5169
  • [2] The stabilization and bio-functionalization of iron oxide nanoparticles using heterotelechelic polymers
    Boyer, Cyrille
    Bulmus, Volga
    Priyanto, Priyanto
    Teoh, Wey Yang
    Amal, Rose
    Davis, Thomas P.
    [J]. JOURNAL OF MATERIALS CHEMISTRY, 2009, 19 (01) : 111 - 123
  • [3] Ultrasensitive magnetic biosensor for homogeneous immunoassay
    Chemla, YR
    Crossman, HL
    Poon, Y
    McDermott, R
    Stevens, R
    Alper, MD
    Clarke, J
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (26) : 14268 - 14272
  • [4] Recent advances in iron oxide nanocrystal technology for medical imaging
    Corot, Claire
    Robert, Philippe
    Idee, Jean-Marc
    Port, Marc
    [J]. ADVANCED DRUG DELIVERY REVIEWS, 2006, 58 (14) : 1471 - 1504
  • [5] Coupling agent effect on magnetic properties of functionalized magnetite-based nanoparticles
    Daou, T. J.
    Greneche, J. M.
    Pourroy, G.
    Buathong, S.
    Derory, A.
    Ulhaq-Bouillet, C.
    Donnio, B.
    Guillon, D.
    Begin-Colin, S.
    [J]. CHEMISTRY OF MATERIALS, 2008, 20 (18) : 5869 - 5875
  • [6] Investigation of the grafting rate of organic molecules on the surface of magnetite nanoparticles as a function of the coupling agent
    Daou, T. J.
    Buathong, S.
    Ung, D.
    Donnio, B.
    Pourroy, G.
    Guillon, D.
    Begin, S.
    [J]. SENSORS AND ACTUATORS B-CHEMICAL, 2007, 126 (01) : 159 - 162
  • [7] Phosphate adsorption properties of magnetite-based nanoparticles
    Daou, T. J.
    Begin-Colin, S.
    Greneche, J. M.
    Thomas, F.
    Derory, A.
    Bernhardt, P.
    Legare, P.
    Pourroy, G.
    [J]. CHEMISTRY OF MATERIALS, 2007, 19 (18) : 4494 - 4505
  • [8] Hydrothermal synthesis of monodisperse magnetite nanoparticles
    Daou, T. J.
    Pourroy, G.
    Begin-Colin, S.
    Greneche, J. M.
    Ulhaq-Bouillet, C.
    Legare, P.
    Bernhardt, P.
    Leuvrey, C.
    Rogez, G.
    [J]. CHEMISTRY OF MATERIALS, 2006, 18 (18) : 4399 - 4404
  • [9] Water soluble dendronized iron oxide nanoparticles
    Daou, T. J.
    Pourroy, G.
    Greneche, J. M.
    Bertin, A.
    Felder-Flesch, D.
    Begin-Colin, S.
    [J]. DALTON TRANSACTIONS, 2009, (23) : 4442 - 4449
  • [10] Drug delivery and nanoparticles: Applications and hazards
    De Jong, Wim H.
    Borm, Paul J. A.
    [J]. INTERNATIONAL JOURNAL OF NANOMEDICINE, 2008, 3 (02): : 133 - 149