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Epidemiology and Challenges of HBV/HIV Co-Infection Amongst HIV-Infected Patients in Endemic Areas: Review
被引:23
作者:
Weldemhret, Letebrhan
[1
]
机构:
[1] Tigray Hlth Res Inst, Med Microbiol, Mekelle, Ethiopia
关键词:
epidemiology;
HBV;
HIV;
HBV-HIV;
co-infection;
patient;
endemic;
HEPATITIS-B-VIRUS;
VIRAL-HEPATITIS;
C VIRUS;
OUTCOMES;
D O I:
10.2147/HIV.S273649
中图分类号:
R51 [传染病];
学科分类号:
100401 ;
摘要:
With the introduction of highly active antiretroviral treatment, HIV-related morbidity and mortality have declined. But underlying hepatitis B virus infection remains the major cause of AIDS-defined illness and liver-related disease progression mainly in endemic settings. Moreover, HBV-HIV co-infection is the leading cause of cirrhosis, hepatocellular carcinoma, and liver-related death. This review paper emphasizes reviewing the burden and impact of HBV-HIV co-infection in liver-related disease progression, immune recovery, and therapeutic management of HIV-infected individuals on ART regimen.
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页码:485 / 490
页数:6
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