Epidemiology and Challenges of HBV/HIV Co-Infection Amongst HIV-Infected Patients in Endemic Areas: Review

被引:23
作者
Weldemhret, Letebrhan [1 ]
机构
[1] Tigray Hlth Res Inst, Med Microbiol, Mekelle, Ethiopia
关键词
epidemiology; HBV; HIV; HBV-HIV; co-infection; patient; endemic; HEPATITIS-B-VIRUS; VIRAL-HEPATITIS; C VIRUS; OUTCOMES;
D O I
10.2147/HIV.S273649
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
With the introduction of highly active antiretroviral treatment, HIV-related morbidity and mortality have declined. But underlying hepatitis B virus infection remains the major cause of AIDS-defined illness and liver-related disease progression mainly in endemic settings. Moreover, HBV-HIV co-infection is the leading cause of cirrhosis, hepatocellular carcinoma, and liver-related death. This review paper emphasizes reviewing the burden and impact of HBV-HIV co-infection in liver-related disease progression, immune recovery, and therapeutic management of HIV-infected individuals on ART regimen.
引用
收藏
页码:485 / 490
页数:6
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