Value of Stress Myocardial Perfusion Scanning in Diagnosis of Severe Coronary Artery Disease in Liver Transplantation Candidates

被引:43
|
作者
Aydinalp, A. [1 ]
Bal, U. [1 ]
Atar, I. [1 ]
Ertan, C. [1 ]
Aktas, A. [2 ]
Yildirir, A. [1 ]
Ozin, B. [1 ]
Mudderisoglu, H. [1 ]
Haberal, M. [3 ]
机构
[1] Baskent Univ, Fac Med, Dept Cardiol, TR-06490 Ankara, Turkey
[2] Baskent Univ, Fac Med, Dept Nucl Med, TR-06490 Ankara, Turkey
[3] Baskent Univ, Fac Med, Dept Gen Surg, TR-06490 Ankara, Turkey
关键词
ECHOCARDIOGRAPHY; DEATH;
D O I
10.1016/j.transproceed.2009.06.219
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Background. The significant potential for perioperative and late cardiovascular complications makes careful preoperative cardiac risk assessment imperative in liver transplantation candidates. Objective. To determine the sensitivity and specificity of myocardial perfusion scanning for detection of coronary artery disease (CAD) in liver transplantation candidates. Patients and Methods. We prospectively evaluated 93 liver transplantation candidates. Patients with known CAD were excluded. All patients, regardless of symptoms and risk factors, underwent myocardial perfusion scanning and coronary angiography. Results. Results of myocardial perfusion scanning were abnormal in 64 patients (68.8%) and normal in 29 patients (31.2%). Of patients with abnormal scans, only 6 (9.4%) had severe CAD at coronary angiography. None of the 29 patients with normal perfusion scans and the 24 patients with fixed defects had severe CAD; however, 6 of 40 patients (15.0%) with reversible perfusion defects had severe CAD at coronary angiography (P = .005). Alcoholic liver disease, reversible perfusion defects at myocardial perfusion scanning, left ventricular systolic dysfunction, and higher low-density lipoprotein (LDL) cholesterol and triglyceride levels were significantly associated with CAD. Defining reversible perfusion defects as a sign of ischemia, and fixed defects and normal perfusion as nonischemic, myocardial perfusion scanning had 100% sensitivity but 61% specificity for severe CAD. The test's accuracy was low (38%). Conclusions. The results of reversible perfusion defects on myocardial perfusion scanning were sensitive but not specific for CAD in liver transplantation candidates. The high number of false-positive results decreased the test's accuracy.
引用
收藏
页码:3757 / 3760
页数:4
相关论文
共 50 条
  • [21] Long-term prognostic value of coronary artery calcium scanning, coronary computed tomographic angiography and stress myocardial perfusion imaging in patients with suspected coronary artery disease
    Carmela Nappi
    Emanuele Nicolai
    Stefania Daniele
    Wanda Acampa
    Valeria Gaudieri
    Roberta Assante
    Emilia Zampella
    Sabrina Segreto
    Massimo Imbriaco
    Mario Petretta
    Marco Salvatore
    Alberto Cuocolo
    Journal of Nuclear Cardiology, 2018, 25 : 833 - 841
  • [22] Incremental value of CT perfusion in the diagnosis of coronary artery disease
    Mordi, Ify
    Tzemos, Nikolaos
    EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, 2013, 14 (05) : 504 - 504
  • [23] SERIAL EXERCISE THALLIUM MYOCARDIAL PERFUSION SCANNING AND EXERCISE ELECTROCARDIOGRAPHY IN THE DIAGNOSIS OF CORONARY-ARTERY DISEASE
    DUNN, RF
    KELLY, DT
    BAILEY, IK
    UREN, R
    MCLAUGHLIN, A
    AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 1979, 9 (05): : 547 - 553
  • [24] Impact of hypertension on the accuracy of exercise stress myocardial perfusion imaging for the diagnosis of coronary artery disease
    Elhendy, A
    Sozzi, F
    van Domburg, R
    Geleijnse, M
    Bax, J
    Kasprzak, J
    Roelandt, J
    EUROPEAN HEART JOURNAL, 2000, 21 : 618 - 618
  • [25] Impact of hypertension on the accuracy of exercise stress myocardial perfusion imaging for the diagnosis of coronary artery disease
    Elhendy, A
    van Domburg, RT
    Sozzi, FB
    Poldermans, D
    Bax, JJ
    Roelandt, JRTC
    HEART, 2001, 85 (06) : 655 - 661
  • [26] SPECT myocardial perfusion imaging in liver transplantation candidates
    W. Lane Duvall
    Aditi Singhvi
    Nidhi Tripathi
    Milena J. Henzlova
    Journal of Nuclear Cardiology, 2020, 27 : 254 - 265
  • [27] SPECT myocardial perfusion imaging in liver transplantation candidates
    Duvall, W. Lane
    Singhvi, Aditi
    Tripathi, Nidhi
    Henzlova, Milena J.
    JOURNAL OF NUCLEAR CARDIOLOGY, 2020, 27 (01) : 254 - 265
  • [28] Contrast Stress Echocardiography for the Diagnosis of Coronary Artery Disease in Patients With Chest Pain but Without Acute Coronary Syndrome: Incremental Value of Myocardial Perfusion
    Gaibazzi, Nicola
    Reverberi, Claudio
    Squeri, Angelo
    De Iaco, Giuseppe
    Ardissino, Diego
    Gherli, Tiziano
    JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 2009, 22 (04) : 404 - 410
  • [29] Myocardial Perfusion and Viability Imaging in Coronary Artery Disease: Clinical Value in Diagnosis, Prognosis, and Therapeutic Guidance
    Li, Dan L.
    Kronenberg, Marvin W.
    AMERICAN JOURNAL OF MEDICINE, 2021, 134 (08): : 968 - 975
  • [30] Prevalence of coronary artery disease evaluated by direct coronary angiography in liver transplantation candidates
    Mircoli, L.
    Vecchiato, C.
    Pernigotti, A.
    Antonelli, B.
    Danzi, G. B.
    Diehl, L.
    Donato, M. F.
    Pomidossi, G.
    Sozzi, F.
    Lombardi, F.
    EUROPEAN HEART JOURNAL, 2014, 35 : 661 - 661