Differential effects of propofol and isoflurane on the relationship between EEG Narcotrend index and clinical stages of anaesthetic depth in sheep undergoing experimental cardiac surgery

被引:2
|
作者
Otto, Klaus A. [1 ]
机构
[1] Hannover Med Sch, Cent Lab Anim Facil, Carl Neuberg Str 1, D-30625 Hannover, Germany
关键词
Electroencephalogram; Narcotrend index; Propofol; Isoflurane; Sheep; GENERAL-ANESTHESIA; ALFENTANIL; MIDAZOLAM;
D O I
10.1016/j.tvjl.2015.10.049
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The electroencephalogram (EEG) Narcotrend index (NI) has been shown to improve anaesthetic depth monitoring in isoflurane-anaesthetised sheep. Data obtained from 13 anaesthetised juvenile female sheep were analysed retrospectively in order to assess the relationship between clinical stages of anaesthesia (CS) and NI during both propofol and isoflurane anaesthesia. Polynomial regression analysis revealed no significant association between CS and NI for propofol (R = 0.374, R-2 = 0.140, P = 0.403) but for isoflurane anaesthesia (R = 0.548, R-2 = 0301, P = 0.010) there was a significant relationship. Furthermore, a strong correlation existed between end-tidal isoflurane concentration (ISOET) and CS (r = -0.463, P = 0.008). A combination of assessment of clinical signs and analogous EEG patterns is recommended during propofol anaesthesia. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码:87 / 89
页数:3
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