Malignant teratoma of the thyroid with predominantly neuroepithelial differentiation -: Fine needle aspiration cytologic, histologic and immunocytochemical features of a case

被引:10
作者
Jayaram, G [1 ]
Cheah, PL
Yip, CH
机构
[1] Univ Malaya, Fac Med, Dept Pathol, Kuala Lumpur 50603, Malaysia
[2] Univ Malaya, Fac Med, Dept Surg, Kuala Lumpur 50603, Malaysia
关键词
teratoma; thyroid neoplasms; aspiration biopsy;
D O I
10.1159/000328481
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
BACKGROUND: Teratoma of the thyroid in adults is extremely rare, and most are malignant. Only nine cases have been adequately documented in the English-language literature, and there ave no reports detailing the fine needle aspiration (FNA) cytologic characteristics. CASE: A 32-year-old-female presented with a left-sided nodular thyroid mass with left cervical lymphadenopathy. FNA cytology of the thyroid and lymph nodes was done. The cytologic and immunocytochemical features were that of a small round cell tumor with neuroepithelial (NE) differentiation, metastasizing to the cervical nones. Microscopic study of the thyroidectomy specimen showed a tumor showing an NE pattern with occasional islands of squamous and cuboidal epithelium, leading to a diagnosis of malignant teratoma. CONCLUSION: Knowledge of FNA cytologic features of rare but highly malignant lesions like thyroid teratomas allow early recognition so that suitable and possibly aggressive treatment protocols can be adopted in the hope of prolonging survival.
引用
收藏
页码:375 / 379
页数:5
相关论文
共 9 条
  • [1] BALE GF, 1950, AM J PATHOL, V26, P565
  • [2] BOWKER CM, 1992, HISTOPATHOLOGY, V21, P81
  • [3] BUCKLEY NJ, 1986, SURGERY, V100, P932
  • [4] MALIGNANT TERATOMA IN THE THYROID GLAND OF AN ADULT
    BUCKWALTER, JA
    LAYTON, JM
    [J]. ANNALS OF SURGERY, 1954, 139 (02) : 218 - 223
  • [5] De May RM, 1996, ART SCI CYTOPATHOLOG, P703
  • [6] HAJDU SI, 1967, ARCH PATHOL, V83, P567
  • [7] KIMLER SC, 1978, CANCER-AM CANCER SOC, V42, P311, DOI 10.1002/1097-0142(197807)42:1<311::AID-CNCR2820420147>3.0.CO
  • [8] 2-V
  • [9] TERATOMAS OF NECK
    STONE, HH
    HENDERSO.D
    GUIDIO, FA
    [J]. AMERICAN JOURNAL OF DISEASES OF CHILDREN, 1967, 113 (02): : 222 - &