YADA: a tool for taking the most out of high-resolution spectra

被引:65
作者
Carvalho, Paulo C. [1 ,2 ]
Xu, Tao [2 ]
Han, Xuemei [2 ]
Cociorva, Daniel [2 ]
Barbosa, Valmir C. [1 ]
Yates, John R., III [2 ]
机构
[1] Univ Fed Rio de Janeiro, COPPE, Syst Engn & Comp Sci Program, BR-21941972 Rio De Janeiro, Brazil
[2] Scripps Res Inst, Dept Physiol Chem, La Jolla, CA 92037 USA
基金
美国国家卫生研究院;
关键词
TANDEM MASS-SPECTRA; PROTEIN IDENTIFICATION; SPECTROMETRY; DATABASE;
D O I
10.1093/bioinformatics/btp489
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
YADA can deisotope and decharge high-resolution mass spectra from large peptide molecules, link the precursor monoisotopic peak information to the corresponding tandem mass spectrum, and account for different co-fragmenting ion species (multiplexed spectra). We describe how YADA enables a pipeline consisting of ProLuCID and DTASelect for analyzing large-scale middle-down proteomics data.
引用
收藏
页码:2734 / 2736
页数:3
相关论文
共 16 条
[1]   Tandem Mass Spectrometry with Ultrahigh Mass Accuracy Clarifies Peptide Identification by Database Retrieval [J].
Boyne, Michael T., II ;
Garcia, Benjamin A. ;
Li, Mingxi ;
Zamdborg, Leonid ;
Wenger, Craig D. ;
Babai, Shannee ;
Kelleher, Neil L. .
JOURNAL OF PROTEOME RESEARCH, 2009, 8 (01) :374-379
[2]   Charge Prediction Machine: Tool for Inferring Precursor Charge States of Electron Transfer Dissociation Tandem Mass Spectra [J].
Carvalho, Paulo C. ;
Cociorva, Daniel ;
Wong, Catherine C. L. ;
Carvalho, Maria da Gloria da C. ;
Barbosa, Valmir C. ;
Yates, John R., III .
ANALYTICAL CHEMISTRY, 2009, 81 (05) :1996-2003
[3]   PatternLab for proteomics: a tool for differential shotgun proteomics [J].
Carvalho, Paulo C. ;
Fischer, Juliana Sg ;
Chen, Emily I. ;
Yates, John R., III ;
Barbosa, Valmir C. .
BMC BIOINFORMATICS, 2008, 9 (1)
[4]   Automated charge state determination of complex isotope-resolved mass spectra by peak-target Fourier transform [J].
Chen, Li ;
Yap, Yee Leng .
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2008, 19 (01) :46-54
[5]   Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry [J].
Chi, An ;
Huttenhower, Curtis ;
Geer, Lewis Y. ;
Coon, Joshua J. ;
Syka, John E. P. ;
Bai, Dina L. ;
Shabanowitz, Jeffrey ;
Burke, Daniel J. ;
Troyanskaya, Olga G. ;
Hunt, Donald F. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (07) :2193-2198
[6]  
Cociorva Daniel, 2007, Curr Protoc Bioinformatics, VChapter 13, DOI 10.1002/0471250953.bi1304s16
[7]   AN APPROACH TO CORRELATE TANDEM MASS-SPECTRAL DATA OF PEPTIDES WITH AMINO-ACID-SEQUENCES IN A PROTEIN DATABASE [J].
ENG, JK ;
MCCORMACK, AL ;
YATES, JR .
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 1994, 5 (11) :976-989
[8]  
Forbes AJ, 2001, PROTEOMICS, V1, P927, DOI 10.1002/1615-9861(200108)1:8<927::AID-PROT927>3.0.CO
[9]  
2-T
[10]   Automated reduction and interpretation of high resolution electrospray mass spectra of large molecules [J].
Horn, DM ;
Zubarev, RA ;
McLafferty, FW .
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2000, 11 (04) :320-332