Efficacy and Safety of a Novel Mouthpiece for Esophagogastroduodenoscopy: A Multi-Center, Randomized Study

被引：2

作者：

Ikebuchi, Yuichiro ^{[1
]}

Matsumoto, Kazuya ^{[1
,2
]}

Ueda, Naoki ^{[2
,3
]}

Yamashita, Taro ^{[1
]}

Kurumi, Hiroki ^{[1
]}

Onoyama, Takumi ^{[1
]}

Takeda, Yohei ^{[1
]}

Yoshida, Akira ^{[1
]}

Kawaguchi, Koichiro ^{[1
]}

Yashima, Kazuo ^{[1
]}

Fujiwara, Kazunori ^{[4
]}

Imamoto, Ryu ^{[3
]}

Noma, Hisashi ^{[5
]}

Ueki, Masaru ^{[6
]}

Isomoto, Hajime ^{[3
]}

机构：

[1] Tottori Univ, Fac Med, Dept Multidisciplinary Internal Med, Div Med & Clin Sci, Tottori 6838504, Japan

[2] Irisawa Med Clin, Hashimoto, Shimane 6900025, Japan

[3] Yasugi Municipal Hosp, Dept Gastroenterol, Yasugi, Shimane 6920404, Japan

[4] Tottori Univ, Fac Med, Dept Otolaryngol Head & Neck Surg, Div Med Sensory & Motor Organs, Tottori 6838504, Japan

[5] Inst Stat Math, Tokyo 1908562, Japan

[6] Tottori Univ Hosp, Adv Med Innovat & Clin Res Ctr, Tottori 6838504, Japan

来源：

DIAGNOSTICS | 2021年 / 11卷 / 03期

关键词：

esophagogastroduodenoscopy (EGD); mouthpiece; visual analog scale; gag reflex; GASTRIC-CANCER; TRANSNASAL; ENDOSCOPY;

D O I：

10.3390/diagnostics11030538

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This randomized trial aimed to compare the safety and efficacy of the GAGLESS mouthpiece for esophagogastroduodenoscopy (EGD) with that of the conventional mouthpiece. In all, 90 participants were divided into the GAGLESS mouthpiece and conventional mouthpiece groups. The primary endpoint was the severity of pain using the visual analog scale (VAS), and secondary endpoints were examination time, past history of endoscopy, success of the procedure, systolic (SBP) and diastolic (DBP) blood pressure, oxygen saturation, pulse rate before and after EGD, and adverse events. Endoscopy was completed in all cases, and no complications were observed. VAS, when passing the scope through the pharynx, was 2.5 +/- 2.4 and 2.0 +/- 1.9 cm (p = 0.24) in the conventional and GAGLESS groups, respectively, and that, throughout the examination, was 2.5 +/- 2.4 and 1.7 +/- 1.5 cm (p = 0.06), respectively. The difference in blood pressure between the GAGLESS and conventional groups was not significant for SBP (p = 0.08) and significant for DBP (p = 0.03). The post-EGD difference in DBP was significantly lower in the GAGLESS group than in the conventional group. The results indicate that GAGLESS mouthpieces had a lower VAS during endoscopy than the conventional mouthpieces, and the changes in blood pressure were smaller with the GAGLESS mouthpiece.

引用

页数：7

共 21 条

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