Meet the corneal myofibroblast: the role of myofibroblast transformation in corneal wound healing and pathology

被引：71
作者：
Myrna, Kathern E. [3 ]
Pot, Simon A. [3 ]
Murphy, Christopher J. [1 ,2 ]
机构：
[1] Univ Calif Davis, Sch Med, Davis, CA 95616 USA
[2] Univ Calif Davis, Sch Vet Med, Davis, CA 95616 USA
[3] Univ Wisconsin, Sch Vet Med, Dept Surg Sci, Madison, WI 53706 USA
来源：
VETERINARY OPHTHALMOLOGY | 2009年 / 12卷
关键词：
cornea; corneal wound healing; myofibroblast; stroma; GROWTH-FACTOR; KERATOCYTE PHENOTYPE; CONFOCAL MICROSCOPY; RADIAL KERATOTOMY; IN-VIVO; DIFFERENTIATION; EXPRESSION; TISSUE; CELLS; PROLIFERATION;
D O I：
10.1111/j.1463-5224.2009.00742.x
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
In recent years the role of the myofibroblast in corneal wound healing has been extensively studied. The transformation of the corneal keratocyte to the fibroblast and myofibroblast phenotypes is a critical process in normal and pathologic corneal wound healing. This review will introduce this important transformation and its role in corneal wound healing and pathology.
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页码：25 / 27
页数：3
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