COVID-19 and Vulnerable Populations in Sub-Saharan Africa

被引：3

作者：

George, J. A. ^{[1
]}

Maphayi, M. R. ^{[1
]}

Pillay, T. ^{[1
]}

机构：

[1] Univ Witwatersrand, Dept Chem Pathol, Natl Hlth Lab Serv, Johannesburg, South Africa

来源：

CLINICAL, BIOLOGICAL AND MOLECULAR ASPECTS OF COVID-19 | 2021年 / 1321卷

关键词：

COVID-19; SARS-CoV-2; Risk factors; Obesity; Diabetes; Hypertension; Kidney disease; HIV tuberculosis; DISEASE; CORONAVIRUS; SARS-COV-2; OBESITY;

D O I：

10.1007/978-3-030-59261-5_13

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The novel corona virus 2019 (COVID-19) outbreak which started in Hubei province in China has now spread to every corner of the earth. While the pandemic started later in Africa, it is now found in all African countries to varying degrees. It is thought that the prevalence and severity of disease is influenced by a number of non-communicable diseases (NCDs) which are all becoming increasingly prevalent in sub-Saharan Africa (SSA). In addition, SSA bears the major burden of human immunodeficiency virus (HIV) and tuberculosis (TB) infections. While data from Europe and the United States show that children are spared severe disease, it is uncertain if the same holds true in SSA where children suffer from sickle cell disease and malnutrition in addition to other infectious diseases. There is limited data from Africa on the effects of these conditions on COVID-19. In this review, we discuss the epidemiology of some of these conditions in Africa and the possible pathogenesis for the interactions of these with COVID-19.

引用

页码：147 / 162

页数：16

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