Adrenal Incidentaloma

被引：179

作者：

Sherlock, Mark ^{[1
,2
]}

Scarsbrook, Andrew ^{[3
]}

Abbas, Afroze ^{[4
]}

Fraser, Sheila ^{[5
]}

Limumpornpetch, Padiporn ^{[6
]}

Dineen, Rosemary ^{[1
,2
]}

Stewart, Paul M. ^{[6
]}

机构：

[1] Beaumont Hosp, Dept Endocrinol, Beaumont Rd, Dublin 9, Ireland

[2] Royal Coll Surgeons Ireland, Dublin, Ireland

[3] Leeds Teaching Hosp NHS Trust, St James Univ Hosp, Dept Radiol, Beckett St, Leeds LS9 7TF, W Yorkshire, England

[4] Leeds Teaching Hosp NHS Trust, St James Univ Hosp, Dept Endocrinol, Beckett St, Leeds LS9 7TF, W Yorkshire, England

[5] Leeds Teaching Hosp NHS Trust, St James Univ Hosp, Dept Endocrine Surg, Beckett St, Leeds LS9 7TF, W Yorkshire, England

[6] Univ Leeds, Fac Med & Hlth, Worsley Bldg,Clarendon Way, Leeds LS2 9NL, W Yorkshire, England

来源：

ENDOCRINE REVIEWS | 2020年 / 41卷 / 06期

关键词：

adrenal adenoma; adrenal incidentaloma; adrenal computed tomography; autonomous cortisol secretion; adrenal cortical carcinoma; SUBCLINICAL CUSHINGS-SYNDROME; PROTEIN-KINASE-A; DUAL-ENERGY CT; SPORADIC ADRENOCORTICAL TUMORS; ALDOSTERONE-PRODUCING ADENOMAS; POSITRON-EMISSION-TOMOGRAPHY; CLINICAL-PRACTICE GUIDELINE; TANDEM MASS-SPECTROMETRY; NIGHT SALIVARY CORTISOL; URINARY FREE CORTISOL;

D O I：

10.1210/endrev/bnaa008

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

An adrenal incidentaloma is now established as a common endocrine diagnosis that requires a multidisciplinary approach for effective management. The majority of patients can be reassured and discharged, but a personalized approach based upon image analysis, endocrine workup, and clinical symptoms and signs are required in every case. Adrenocortical carcinoma remains a real concern but is restricted to <2% of all cases. Functional adrenal incidentaloma lesions are commoner (but still probably <10% of total) and the greatest challenge remains the diagnosis and optimum management of autonomous cortisol secretion. Modern-day surgery has improved outcomes and novel radiological and urinary biomarkers will improve early detection and patient stratification in future years to come.

引用

页码：775 / 820

页数：46

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