A Simple Method for the Synthesis of 3-Arylthieno[2,3-b]pyridines via Iodine-Mediated Cyclization of 3-(1-Arylalkenyl)-2-[(1-phenylethyl)sulfanyl]pyridines

被引：7

作者：

Kobayashi, Kazuhiro ^{[1
]}

Nakamura, Daizo ^{[1
]}

Shiroyama, Yasuhiko ^{[1
]}

Fukamachi, Shuhei ^{[1
]}

Konishi, Hisatoshi ^{[1
]}

机构：

[1] Tottori Univ, Grad Sch Engn, Dept Chem & Biotechnol, Div Appl Chem, Tottori 6808552, Japan

来源：

SYNTHESIS-STUTTGART | 2009年 / 13期

关键词：

thieno[2,3-b]pyridines; iodine; 2-bromopyridines; cyclization; heterocycles; PYRIDINE; THIENOPYRIDINE; DERIVATIVES; AGENTS;

D O I：

10.1055/s-0029-1216857

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3-Arylthieno[2,3-b]pyridines are synthesized in a short four-step sequence from readily available 2-bromopyridines. The final and key step of the reported method involves an iodine-mediated 5-endo cyclization of 3-(1-arylalkenyl)-2-[(1-phenylethyl)sulfanyl]pyridines.

引用

页码：2179 / 2183

页数：5

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