Involvement of apolipoprotein E in the hematogenous route of herpes simplex virus type 1 to the central nervous system

被引：52
|
作者：
Burgos, JS
Ramirez, C
Sastre, I
Bullido, MJ
Valdivieso, F
机构：
[1] Univ Autonoma Madrid, CSIC, Dept Biol Mol, E-28049 Madrid, Spain
[2] Univ Autonoma Madrid, CSIC, Ctr Biol Mol Severo Ochoa, E-28049 Madrid, Spain
来源：
JOURNAL OF VIROLOGY | 2002年 / 76卷 / 23期
关键词：
D O I：
10.1128/JVI.76.23.12394-12398.2002
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Apolipoprotein E (ApoE), a constituent of the lipoproteins, may be relevant in herpes simplex virus type 1 (HSV-1) infection of the central nervous system (CNS), since HSV-1 binds to human serum ApoE lipoproteins. This study demonstrates the involvement of ApoE in the hematogenous route of HSV-1 to the CNS.
引用
收藏
页码：12394 / 12398
页数：5
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