FOXP3 GENE TRANSFER CONVERTS FOXP3-MUTATED EFFECTOR T CELLS INTO REGULATORY T CELLS: TOWARDS GENE THERAPY FOR IPEX SYNDROME

被引：0
|
作者：
Passerini, Laura [1 ]
Fousteri, Georgia [2 ]
Mel, Eva Rossi [3 ]
Sartirana, Claudia [2 ]
Naldini, Luigi [3 ]
Roncarolo, M. G. [4 ]
Bacchetta, Rosa [1 ]
机构：
[1] San Raffaele Telethon Inst Gene Therapy HSR TIGET, Milan, Italy
[2] Ist Sci San Raffaele, Milan, Italy
[3] San Raffaele Scietif Inst, Dept Regenerat Med, San Raffaele Telethon Inst Gene Therapy, Milan, Italy
[4] Univ Vita Salute San Raffaele, Milan, Italy
来源：
JOURNAL OF CLINICAL IMMUNOLOGY | 2013年 / 33卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页码：673 / 673
页数：1
相关论文
共 50 条
  • [31] Epigenetic control of the foxp3 locus in regulatory T cells
    Floess, Stefan
    Freyer, Jennifer
    Siewert, Christiane
    Baron, Udo
    Olek, Sven
    Polansky, Julia
    Schlawe, Kerstin
    Chang, Hyun-Dong
    Bopp, Tobias
    Schmitt, Edgar
    Klein-Hessling, Stefan
    Serfling, Edgar
    Hamann, Alf
    Huehn, Jochen
    PLOS BIOLOGY, 2007, 5 (02) : 169 - 178
  • [32] Foxp3 controls oxidative phosphorylation in regulatory T cells
    Beier, Ulf H.
    Angelin, Alessia
    Jiao, Jing
    Xiao, Haiyan
    Wang, Liqing
    Dahiya, Satinder
    Wells, Andrew D.
    Wallace, Douglas C.
    Hancock, Wayne W.
    JOURNAL OF IMMUNOLOGY, 2016, 196
  • [33] Role of regulatory T cells and FOXP3 in human diseases
    Bacchetta, Rosa
    Gambineri, Eleonora
    Roncarolo, Maria-Grazia
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 120 (02) : 227 - 235
  • [34] Functional reprogramming of regulatory T cells in the absence of Foxp3
    Charbonnier, Louis-Marie
    Lopez, David
    Bleesing, Jacob
    Garcia-Lloret, Maria
    Chen, Karin
    Ozen, Ahmet
    Li, Ming
    Pellegrini, Matteo
    Chatila, Talal A.
    JOURNAL OF IMMUNOLOGY, 2018, 200 (01):
  • [35] Regulatory T Cells in Pregnancy: It Is Not All About FoxP3
    Krop, Juliette
    Heidt, Sebastiaan
    Claas, Frans H. J.
    Eikmans, Michael
    FRONTIERS IN IMMUNOLOGY, 2020, 11
  • [36] Functional reprogramming of regulatory T cells in the absence of Foxp3
    Charbonnier, Louis-Marie
    Cui, Ye
    Stephen-Victor, Emmanuel
    Harb, Hani
    Lopez, David
    Bleesing, Jack J.
    Garcia-Lloret, Maria, I
    Chen, Karin
    Ozen, Ahmet
    Carmeliet, Peter
    Li, Ming O.
    Pellegrini, Matteo
    Chatila, Talal A.
    NATURE IMMUNOLOGY, 2019, 20 (09) : 1208 - +
  • [37] IPEX-Like Syndrome: A Quantitative Defect of Regulatory T Cells Detected by Demethylation Analysis of the FOXP3 Locus
    Barzaghi, F.
    Passerini, L.
    Gambineri, E.
    Mannurita, S. Ciullini
    Cornu, T.
    Kang, E. S.
    Choe, Y. H.
    Cancrini, C.
    Ciccocioppo, R.
    Ikinciogullari, A.
    Roncarolo, M. G.
    Olek, S.
    Bacchetta, R.
    JOURNAL OF CLINICAL IMMUNOLOGY, 2012, 32 (02) : 376 - 376
  • [38] Functional reprogramming of regulatory T cells in the absence of Foxp3
    Louis-Marie Charbonnier
    Ye Cui
    Emmanuel Stephen-Victor
    Hani Harb
    David Lopez
    Jack J. Bleesing
    Maria I. Garcia-Lloret
    Karin Chen
    Ahmet Ozen
    Peter Carmeliet
    Ming O. Li
    Matteo Pellegrini
    Talal A. Chatila
    Nature Immunology, 2019, 20 : 1208 - 1219
  • [39] CREMALPHA DESTABILIZES FOXP3 EXPRESSION IN REGULATORY T CELLS
    Ohl, K.
    Rauen, T.
    Tenbrock, K.
    ANNALS OF THE RHEUMATIC DISEASES, 2013, 71 : 71 - 71
  • [40] Demethylation analysis of the FOXP3 locus shows quantitative defects of regulatory T cells in IPEX-like syndrome
    Barzaghi, F.
    Passerini, L.
    Gambineri, E.
    Mannurita, S. Ciullini
    Cornu, T.
    Kang, E. S.
    Choe, Y. H.
    Cancrini, C.
    Corrente, S.
    Ciccocioppo, R.
    Cecconi, M.
    Zuin, G.
    Discepolo, V.
    Sartirana, C.
    Schmidtko, J.
    Ikinciogullari, A.
    Ambrosi, A.
    Roncarolo, M. G.
    Olek, S.
    Bacchetta, R.
    JOURNAL OF AUTOIMMUNITY, 2012, 38 (01) : 49 - 58
12345