CD147 in regulatory T cells

被引：36

作者：

Landskron, Johannes ^{[1
,2
,3
]}

Tasken, Kjetil ^{[1
,2
,3
,4
]}

机构：

[1] Univ Oslo, Ctr Mol Med Norway, Nordic EMBL Partnership, N-0318 Oslo, Norway

[2] Oslo Univ Hosp, N-0318 Oslo, Norway

[3] Univ Oslo, Ctr Biotechnol, N-0317 Oslo, Norway

[4] Oslo Univ Hosp, Dept Infect Dis, N-0407 Oslo, Norway

来源：

CELLULAR IMMUNOLOGY | 2013年 / 282卷 / 01期

关键词：

Regulatory T cells; FoxP3; CD147; Treg purification; IMMUNOGLOBULIN SUPERFAMILY; CYCLOPHILIN-B; HIV-1; INFECTION; ACTIVATION; EXPRESSION; ADHESION; FOXP3; PROLIFERATION; EMMPRIN; MEMBER;

D O I：

10.1016/j.cellimm.2013.04.008

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

CD147 or EMMPRIN belongs to the immunoglobulin superfamily of membrane receptors and is expressed in epithelial cells, cancer cells and T cells of the immune system. In T cells CD147 functions as a receptor for soluble cyclophilins and is involved in chemotaxis. We recently reported its expression to high levels and association with suppressive function in regulatory T cells. Here, we discuss its potential application as a marker of activated regulatory T cells. (C) 2013 Elsevier Inc. All rights reserved.

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页码：17 / 20

页数：4

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