Examination of the Phenolic Profile and Antioxidant Activity of the Leaves of the Australian Native Plant Smilax glyciphylla

被引:13
作者
Huang, An-Cheng [1 ]
Wilde, Amelie [2 ]
Ebmeyer, Johanna [2 ]
Skouroumounis, George K. [1 ]
Taylor, Dennis K. [1 ]
机构
[1] Univ Adelaide, Sch Agr Food & Wine, Adelaide, SA 5064, Australia
[2] Tech Univ Carolo Wilhelmina Braunschweig, Inst Food Chem, D-38114 Braunschweig, Germany
来源
JOURNAL OF NATURAL PRODUCTS | 2013年 / 76卷 / 10期
关键词
APOPTOSIS; CELLS; FLAVONOIDS; POWER;
D O I
10.1021/np4005163
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Together with the sweet principle component glycyphyllin A (3), seven phenolic compounds including two new dihydrochalcone rhamnopyranosides, glycyphyllin B (1) and glycyphyllin C (2), and five known flavonoids, catechin (4), kaempferol-3-O-beta-D-glucopyranoside (5), quercetin-3-O-beta-D-glucopyranoside (6), kaempferol-3-O-beta-neohesperidoside (7), and 2R,3R-dihydrokaempferol-3-O-beta-D-glucopyranoside (8), have been isolated from the ethanolic extract of the leaves of Smilax glyciphylla for the first time. The structures of these compounds were characterized by spectroscopic methods including UV, MS, and ID and 2D NMR In vitro antioxidant capacity tests employing FRAP and DPPH assays indicated that 1, 4, and 6 exhibited potent antioxidant activity and are the key phenolics responsible for the antioxidant activity of the leaf extract of S. glyciphylla.
引用
收藏
页码:1930 / 1936
页数:7
相关论文
共 21 条
[1]   Isolation and characterization of novel benzoates, cinnamates, flavonoids, and lignans from Riesling wine and screening for antioxidant activity [J].
Baderschneider, B ;
Winterhalter, P .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2001, 49 (06) :2788-2798
[2]   The ferric reducing ability of plasma (FRAP) as a measure of ''antioxidant power'': The FRAP assay [J].
Benzie, IFF ;
Strain, JJ .
ANALYTICAL BIOCHEMISTRY, 1996, 239 (01) :70-76
[3]  
BRAND-WILLIAMS W, 1995, FOOD SCI TECHNOL-LEB, V28, P25
[4]   Mitochondrial free radical generation, oxidative stress, and aging [J].
Cadenas, E ;
Davies, KJA .
FREE RADICAL BIOLOGY AND MEDICINE, 2000, 29 (3-4) :222-230
[5]   Antioxidant activity in Australian native sarsaparilla (Smilax glyciphylla) [J].
Cox, SD ;
Jayasinghe, KC ;
Markham, JL .
JOURNAL OF ETHNOPHARMACOLOGY, 2005, 101 (1-3) :162-168
[6]   Catechin and epicatechin deprotonation followed by 13C NMR [J].
Cren-Olivé, C ;
Wieruszeski, JM ;
Maes, E ;
Rolando, C .
TETRAHEDRON LETTERS, 2002, 43 (25) :4545-4549
[7]   Free radical-induced damage to DNA: Mechanisms and measurement [J].
Dizdaroglu, M ;
Jaruga, P ;
Birincioglu, M ;
Rodriguez, H .
FREE RADICAL BIOLOGY AND MEDICINE, 2002, 32 (11) :1102-1115
[8]   SYNTHESIS OF GLYCYPHYLLIN [J].
ESAKI, S ;
ABE, M ;
SHIBA, N ;
KAMIYA, S .
AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1990, 54 (06) :1583-1585
[9]   Free radicals, antioxidants, and nutrition [J].
Fang, YZ ;
Yang, S ;
Wu, GY .
NUTRITION, 2002, 18 (10) :872-879
[10]   Evaluation of the antioxidant activity of flavonoids by "ferric reducing antioxidant power" assay and cyclic voltammetry [J].
Firuzi, O ;
Lacanna, A ;
Petrucci, R ;
Marrosu, G ;
Saso, L .
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2005, 1721 (1-3) :174-184