RNA Binding: Getting Specific about Specificity

被引：5

作者：

Ferre-D'Amare, Adrian R. ^{[1
]}

机构：

[1] NHLBI, 50 South Dr,MSC 8012, Bethesda, MD 20892 USA

来源：

CELL CHEMICAL BIOLOGY | 2016年 / 23卷 / 10期

关键词：

TRANSLATIONAL INITIATION SITES; ESCHERICHIA-COLI; LANDSCAPES; PROTEIN;

D O I：

10.1016/j.chembiol.2016.10.001

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Sequence-specific nucleic acid binding proteins do not recognize one sequence out of all possibilities; rather, they bind to many sequences with a range of affinities. In this issue of Cell Chemical Biology, Lin et al. (2016), describe the entire landscape of affinities between different RNA molecules and an RNA-binding protein, thus providing a comprehensive description of the factors affecting specificity.

引用

页码：1177 / 1178

页数：2

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