A Rare Case of Hemoglobin E/Beta-Thalassemia and Systemic Lupus Erythematosus

被引：1
作者：
Khamees, Ibrahim [1 ]
Obeidat, Ibrahim Mohammad [1 ]
Rozi, Waail [1 ]
Yassin, Mohamed A. [2 ]
机构：
[1] Hamad Med Corp, Internal Med, Doha, Qatar
[2] Hamad Gen Hosp, Hematol & Oncol, Doha, Qatar
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2020年 / 12卷 / 09期
关键词：
systemic lupus erythematosus; hemolytic anemia; hemoglobin e/beta-thalassemia; TRAIT;
D O I：
10.7759/cureus.10332
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease, with multisystemic involvement. Hemoglobin E/beta-thalassemia (HbE/beta-thalassemia) is the genotype responsible for approximately one-half of all severe beta-thalassemia worldwide. When beta-thalassemia and SLE coexist, SLE seems to have a more severe course. Here we report a 32-year-old female who presented with dizziness and fatigue was found to have severe hemolytic anemia with thrombocytopenia. Upon further evaluation, she was diagnosed with HbE/beta-thalassemia and SLE, which is a very rare association. In SLE patients, anemia usually results from the disease itself, but it is important to think of other coexisting conditions like thalassemia.
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