Total synthesis of racemic 1-aryl-tetrahydroisoquinoline alkaloids

被引：1
|
作者：
Abranyi-Balogh, Peter [1 ]
Foeldesi, Tamas [1 ]
Milen, Matyas [1 ]
机构：
[1] Budapest Univ Technol & Econ, Dept Organ Chem & Technol, Budapest, Hungary
来源：
MONATSHEFTE FUR CHEMIE | 2015年 / 146卷 / 11期
关键词：
Natural products; Heterocycles; Catalysis; Thionation; Liebeskind-Srogl reaction; BETA-CARBOLINE DERIVATIVES; CRYPTOSTYLIS FULVA SCHLTR; ANTI-HIV AGENTS; ORCHIDACEAE ALKALOIDS; ABSOLUTE CONFIGURATION; ASYMMETRIC-SYNTHESIS; TETRAHYDROISOQUINOLINES; CYCLIZATION; ANTAGONISTS; ANALOGS;
D O I：
10.1007/s00706-015-1564-y
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new synthetic route was developed for the preparation of natural products cryptostyline I, II, III and 1-phenyl-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline. The Liebeskind-Srogl palladium-catalyzed carbon-carbon cross-coupling protocol was used in the key step of the total synthesis. [GRAPHICS] .
引用
收藏
页码：1907 / 1912
页数：6
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