In vitro cytotoxic activity of methanolic extract of stem bark of Cassia fistula L.

被引：0
作者：
Linu, Mathew [1 ]
Shankar, Shashidhar [2 ]
机构：
[1] MG Univ, Sch Biosci, Kottayam, Kerala, India
[2] Azeezia Med Coll, Kollam, Kerala, India
来源：
RESEARCH JOURNAL OF BIOTECHNOLOGY | 2012年 / 7卷 / 04期
关键词：
Casssia fistula; MTT; DAPI; Mitosensor; Caspases; human cell lines; CYTOCHROME-C RELEASE; APOPTOSIS; BAX; MITOCHONDRIA; CARCINOMA; PLANTS; CELLS;
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
As part of a permanent screening programme, which considers the search for plants and natural products with anticancer properties, the plants are subjected to bioscreening assay testing for cytotoxity. Another crucial component of pre-clinical oncology drug development is the study and monitoring of cell death in tumour and normal tissues. Therefore, methanolic extract stem bark of cassia fistula L was tested for in vitro cytotoxicity and apoptogenic potential by MTT assay, DAPI assay, mitosensor assay and caspase assay.
引用
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页码：141 / 148
页数：8
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