Visualization of Cerebrospinal Fluid Movement with Spin Labeling at MR Imaging: Preliminary Results in Normal and Pathophysiologic Conditions

被引：123

作者：

Yamada, Shinya ^{[2
]}

Miyazaki, Mitsue ^{[1
]}

Kanazawa, Hitoshi ^{[4
]}

Higashi, Minako ^{[5
]}

Morohoshi, Yukuo ^{[3
]}

Bluml, Stefan ^{[6
,8
]}

McComb, J. Gordon ^{[7
,9
]}

机构：

[1] MR Toshiba Med Res Inst USA, Dept Clin Res, Vernon Hills, IL 60061 USA

[2] Tokai Univ, Oiso Hosp, Dept Neurosurg, Kanagawa 2591100, Japan

[3] Tokai Univ, Oiso Hosp, Dept Radiol, Kanagawa 2591100, Japan

[4] Toshiba Med Syst, MRI Dept, Tochigi, Japan

[5] Toshiba Med Syst, MRI Applicat, Kanagawa, Japan

[6] Childrens Hosp Los Angeles, Dept Radiol, Los Angeles, CA 90027 USA

[7] Univ So Calif, Keck Sch Med, Dept Neurol Surg, Los Angeles, CA 90033 USA

[8] Rudi Schulte Res Inst, Santa Barbara, CA USA

[9] Childrens Hosp Los Angeles, Div Neurosurg, Los Angeles, CA 90027 USA

来源：

RADIOLOGY | 2008年 / 249卷 / 02期

关键词：

D O I：

10.1148/radiol.2492071985

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Institutional review board approval and informed consent were obtained for this study. This study was HIPAA compliant. The purpose of this study was to visualize the movement of cerebrospinal fluid (CSF) noninvasively by using an unenhanced magnetic resonance imaging technique. A time-spatial labeling inversion pulse (SLIP) technique was applied to label, or tag, CSF in a region of interest. The tagged CSF was clearly visualized at inversion times of 1500-4500 msec after pulse labeling in both intracranial and intraspinal compartments. Noninvasive visualization of CSF movement, including bulk and turbulent flow, in normal (n = 7) and altered (n = 2) physiologic conditions was possible by using the unenhanced time-SLIP technique. (c) RSNA, 2008

引用

页码：644 / 652

页数：9

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