Medium-term Survival Following of Stroke in Yaounde (Cameroon): a prospective observational cohort study

Background: With 5.7 million deaths per year, stroke is the second cause of mortality worldwide, and 70% of these deaths occur in developing countries especially in relation to inappropriate clinical pathways and resources. The aim of our study was to assess the survival rate of stroke patients within 90 days and to identify its determinants. Methods: It was a prospective observational cohort study over a period of 90 days after stroke. Patients were recruited between February and May 2015 in two tertiary hospitals in Yaounde. The mortality rate was obtained by the Kaplan-Meier method. Multivariate analysis was performed using a Cox proportional hazards model. Results: Sixty-six patients were enrolled of which 54 were followed up to 90 days. The overall mortality rate was 23.2% (95% CI: 12.5-87.5), more than two-thirds of the deaths occurred within the first 30 days. The mortality rates at days 14, 30, 60 day were 9.1% (95% CI: 3.0-16.7), 14.3% (95% CI: 6.3-23.8) and 21.1% (95% CI: 10.5-31.6) respectively. High systolic blood pressure and a low Glasgow coma score on admission were independent risk factors of mortality at 90 days. Conclusions: The stroke related mortality compels appropriate collective mobilization for an early and adequate management of stroke patients. (c) 2020 Elsevier Inc. All rights reserved.