Decrease in opioid and intra-articular corticosteroid burden after intra-articular hyaluronic acid for knee osteoarthritis treatment

被引：4

作者：

Niazi, Faizan ^{[1
]}

Ong, Kevin L. ^{[2
]}

Kidd, Vasco Deon ^{[3
]}

Lau, Edmund ^{[4
]}

Kurtz, Steven M. ^{[2
]}

Dysart, Stanley H. ^{[5
]}

Malanga, Gerard ^{[6
,7
]}

机构：

[1] Ferring Pharmaceut Inc, 100 Interpace Pkwy, Parsippany, NJ 07054 USA

[2] Exponent Inc, 3440 Market St,Suite 600, Philadelphia, PA 19104 USA

[3] Univ Calif Irvine UCI Hlth, Dept Orthopaed Surg, 101 City Dr South, Orange, CA 92868 USA

[4] Exponent Inc, 149 Commonwealth Ave, Menlo Pk, CA 94025 USA

[5] Pinnacle Orthopaed & Sports Med Specialists, 652 Church St, Marietta, GA 30060 USA

[6] New Jersey Regenerat Inst, 197 Ridgedale Ave 210, Cedar Knolls, NJ 07927 USA

[7] NJ Med Sch Newark, Rutgers Sch Med, Dept Phys Med & Rehabil, Newark, NJ 07109 USA

来源：

PAIN MANAGEMENT | 2020年 / 10卷 / 06期

关键词：

hyaluronic acid; intra-articular corticosteroids; knee arthroplasty; knee osteoarthritis; opioids; PRESCRIBING OPIOIDS; JOINT REPLACEMENT; ARTHROPLASTY; PAIN; IMPACT; GUIDELINE; REVISION;

D O I：

10.2217/pmt-2020-0057

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Aim:We studied changes in opioid prescriptions and corticosteroid injection use for knee osteoarthritis patients before and after intra-articular hyaluronic acid (HA) use and opioid prescriptions before and after knee arthroplasty (KA).Materials & methods: A total of 1,017,578 knee osteoarthritis members were ascertained from a commercial claims database (Health Intelligence Company LLC, IL, USA) using ICD9/ICD10 diagnosis codes.Results: Eighty two percent of HA patients did not fill opioid prescriptions postinjection, with 54% of opioid users discontinuing fills. Two-thirds of KA patients filled opioid prescriptions within 6 months postsurgery, with 78% of opioid users continuing fills and 62% of nonusers initiating use.Conclusion:Alternative therapies, such as HA, that reduce opioid use may alleviate opioid addiction risks for KA patients who use opioids in the pre- and postoperative periods.

引用

页码：387 / 397

页数：11

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