Longitudinal Evaluation of the QuantiFERON-TB Gold Plus Assay in Hospitalized COVID-19 Patients with a First Indeterminate Result: Resolution of Inflammation and Restoration of T-Lymphocyte Counts and Interferon-Gamma Production

被引：7

作者：

Alessio, Grazia ^{[1
]}

Imeneo, Alessandra ^{[1
]}

Di Lorenzo, Andrea ^{[1
]}

Rossi, Benedetta ^{[1
]}

Sorace, Chiara ^{[1
]}

Compagno, Mirko ^{[1
]}

Coppola, Luigi ^{[1
]}

Campogiani, Laura ^{[1
]}

Crea, Angela Maria Antonia ^{[1
]}

Malagnino, Vincenzo ^{[1
]}

Buccisano, Francesco ^{[2
]}

Andreoni, Massimo ^{[1
]}

Sarmati, Loredana ^{[1
]}

Iannetta, Marco ^{[1
]}

机构：

[1] Tor Vergata Univ, Dept Syst Med, Rome, Italy

[2] Tor Vergata Univ, Dept Biomed & Prevent, Rome, Italy

来源：

MICROBIOLOGY SPECTRUM | 2022年 / 10卷 / 05期

关键词：

coronavirus; QuantiFERON; IGRA; tuberculosis; T-lymphocyte; SARS-CoV-2; interferons;

D O I：

10.1128/spectrum.01858-22

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

引用

页数：3

共 12 条

[1] Baseline T-lymphocyte subset absolute counts can predict both outcome and severity in SARS-CoV-2 infected patients: a single center study [J].

Iannetta, Marco ;

Buccisano, Francesco ;

Fraboni, Daniela ;

Malagnino, Vincenzo ;

Campogiani, Laura ;

Teti, Elisabetta ;

Spalliera, Ilaria ;

Rossi, Benedetta ;

Di Lorenzo, Andrea ;

Palmieri, Raffaele ;

Crea, Angela ;

Zordan, Marta ;

Vitale, Pietro ;

Voso, Maria Teresa ;

Andreoni, Massimo ;

Sarmati, Loredana .

SCIENTIFIC REPORTS, 2021, 11 (01)

[2] In Patients with Severe COVID-19, the Profound Decrease in the Peripheral Blood T-Cell Subsets Is Correlated with an Increase of QuantiFERON-TB Gold Plus Indeterminate Rates and Reflecting a Reduced Interferon-Gamma Production [J].

Imeneo, Alessandra ;

Alessio, Grazia ;

Di Lorenzo, Andrea ;

Campogiani, Laura ;

Lodi, Alessandra ;

Barreca, Filippo ;

Zordan, Marta ;

Barchi, Virginia ;

Massa, Barbara ;

Tedde, Simona ;

Crea, Angela ;

Vitale, Pietro ;

Spalliera, Ilaria ;

Compagno, Mirko ;

Coppola, Luigi ;

Dori, Luca ;

Malagnino, Vincenzo ;

Teti, Elisabetta ;

Andreoni, Massimo ;

Sarmati, Loredana ;

Iannetta, Marco .

LIFE-BASEL, 2022, 12 (02)

[3] The (in)significance of TB and COVID-19 co-infection [J].

Khurana, Alkesh Kumar ;

Aggarwal, Deepak .

EUROPEAN RESPIRATORY JOURNAL, 2020, 56 (02)

[4] Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections [J].

Remy, Kenneth E. ;

Mazer, Monty ;

Striker, David A. ;

Ellebedy, Ali H. ;

Walton, Andrew H. ;

Unsinger, Jacqueline ;

Blood, Teresa M. ;

Mudd, Philip A. ;

Yi, Daehan J. ;

Mannion, Daniel A. ;

Osborne, Dale F. ;

Martin, R. Scott ;

Anand, Nitin J. ;

Bosanquet, James P. ;

Blood, Jane ;

Drewry, Anne M. ;

Caldwell, Charles C. ;

Turnbull, Isaiah R. ;

Brakenridge, Scott C. ;

Moldwawer, Lyle L. ;

Hotchkiss, Richard S. .

JCI INSIGHT, 2020, 5 (17)

[5]

Ryu MR, 2018, J CLIN MICROBIOL, V56, DOI [10.1128/jcm.00438-18, 10.1128/JCM.00438-18]

[6] Influence of Cytokine Release Syndrome in Severe COVID-19 Patients Treated With Tocilizumab Over the Quantiferon TB Gold Plus Results [J].

Sanchez-Martinez, Francesca ;

Arenas-Miras, Mar ;

Jove-Caballe, Neus ;

Knobel-Freud, Hernando .

ARCHIVOS DE BRONCONEUMOLOGIA, 2021, 57 :58-59

[7] Elevated Rates of Indeterminate Results on QuantiFERON-TB Gold Plus in COVID-19 Patients [J].

Shier, Kileen L. .

JOURNAL OF CLINICAL MICROBIOLOGY, 2021, 59 (10)

[8] Clinical Significance of Indeterminate QuantiFERON-TB Gold Plus Assay Results in Hospitalized COVID-19 Patients with Severe Hyperinflammatory Syndrome [J].

Solanich, Xavier ;

Fernandez-Huerta, Miguel ;

Basaez, Celeste ;

Antoli, Arnau ;

Rocamora-Blanch, Gemma ;

Corbella, Xavier ;

Santin, Miguel ;

Alcaide, Fernando .

JOURNAL OF CLINICAL MEDICINE, 2021, 10 (05) :1-8

[9] On tuberculosis and COVID-19 co-infection [J].

Tadolini, Marina ;

Garcia-Garcia, Jose-Maria ;

Blanc, Francois-Xavier ;

Borisov, Sergey ;

Goletti, Delia ;

Motta, Ilaria ;

Codecasa, Luigi Ruffo ;

Tiberi, Simon ;

Sotgiu, Giovanni ;

Migliori, Giovanni Battista .

EUROPEAN RESPIRATORY JOURNAL, 2020, 56 (02)

[10] Preliminary observations on IGRA testing for TB infection in patients with severe COVID-19 eligible for immunosuppressive therapy [J].

Torre, Alessandro ;

Aliberti, Stefano ;

Castellotti, Paola Francesca ;

Cirillo, Daniela Maria ;

Grisolia, Antonella ;

Mangioni, Davide ;

Marchetti, Giulia ;

Rossotti, Roberto ;

Santus, Pierachille ;

Besozzi, Giorgio ;

Villa, Simone ;

Codecasa, Luigi Ruffo .

RESPIRATORY MEDICINE, 2020, 175

← 1 2 →