Vinblastine and prednisolone as adjunctive therapy for canine cutaneous mast cell tumors

被引:61
作者
Davies, David R.
Wyatt, Kenneth M.
Jardine, John E.
Robertson, Ian D.
Irwin, Peter J.
机构
[1] Murdoch Univ, Div Vet & Biomed Sci, Murdoch, WA 6150, Australia
[2] Vetpath Lab Serv, Belmont, WA 6984, Australia
关键词
D O I
10.5326/0400124
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Twenty-seven dogs with inadequately excised, cutaneous mast cell tumors (MCT; 20 residual microscopic disease, seven marginal excision) were treated with a vinblastine and prednisolone chemotherapeutic protocol. Twenty dogs were available for follow-up examination after 12 months. One dog suffered local recurrence of the tumor, four dogs developed new cutaneous tumors, and one dog had both events. Fourteen dogs were free of MCT. There was no confirmed tumor-related mortality. Although toxicity from the chemotherapy was generally mild, one dog died of sepsis during treatment.
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页码:124 / 130
页数:7
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