Image-guidedrobotic radiosurgery for glomus jugulare tumors-Multicenter experience and review of the literature

被引:7
作者
Ehret, Felix [1 ]
Kufeld, Markus [1 ]
Fuerweger, Christoph [1 ,2 ]
Haidenberger, Alfred [1 ]
Schichor, Christian [3 ]
Lehrke, Ralph [4 ]
Fichte, Susanne [5 ]
Senger, Carolin [6 ]
Bleif, Martin [7 ]
Ruess, Daniel [2 ]
Ruge, Maximilian [2 ]
Tonn, Joerg-Christian [3 ]
Muacevic, Alexander [1 ]
Hempel, John-Martin [8 ]
机构
[1] European Cyberknife Ctr, Max Lebsche Pl 31, D-81377 Munich, Germany
[2] Univ Hosp Cologne, Ctr Neurosurg, Dept Stereotaxy & Funct Neurosurg, Cologne, Germany
[3] Ludwig Maximilians Univ Munchen, Dept Neurosurg, Campus Grosshadern, Munich, Germany
[4] German CyberKnife Ctr, Soest, Germany
[5] CyberKnife Ctr Mitteldeutschland, Erfurt, Germany
[6] Charite Univ Med Berlin, Charite CyberKnife Ctr, Berlin, Germany
[7] CyberKnife Sudwest, Radiochirurgicum, Goppingen, Germany
[8] Ludwig Maximilians Univ Munchen, Dept Otorhinolaryngol & Head & Neck Surg, Campus Grosshadern, Munich, Germany
来源
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2021年 / 43卷 / 01期
关键词
CyberKnife; glomus jugulare; paraganglioma; radiosurgery; review; GAMMA-KNIFE RADIOSURGERY; STEREOTACTIC RADIOSURGERY; NECK PARAGANGLIOMAS; SURGICAL RESECTION; MANAGEMENT; HEAD; OUTCOMES; SURGERY; RADIOTHERAPY; TOXICITY;
D O I
10.1002/hed.26439
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Background Glomus jugulare tumors (GJTs) are challenging to treat due to their vascularization and location. This analysis evaluates the effectiveness and safety of image-guided robotic radiosurgery (RRS) for GJTs in a multicenter study and reviews the existing radiosurgical literature. Methods We analyzed outcome data from 101 patients to evaluate local control (LC), changes in pretreatment deficits, and toxicity. Moreover, radiosurgical studies for GJTs have been reviewed. Results After a median follow-up of 35 months, the overall LC was 99%. Eighty-eight patients were treated with a single dose, 13 received up to 5 fractions. The median tumor volume was 5.6 cc; the median treatment dose for single-session treatments is 16 Gy, and for multisession treatments is 21 Gy. Fifty-six percentage of patients experienced symptom improvement or recovered entirely. Conclusions RRS is an effective primary and secondary treatment option for GJTs. The available literature suggests that radiosurgery is a treatment option for most GJTs.
引用
收藏
页码:35 / 47
页数:13
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