DNA cleavage activities of (-)-epigallocatechin, (-)-epicatechin, (+)-catechin, and (-)-epigallocatechin gallate with various kind of metal ions

被引：39
作者：
Hayakawa, F
Kimura, T [1 ]
Hoshino, N
Ando, T
机构：
[1] Shiga Univ Med Sci, Dept Chem, Shiga 5202192, Japan
[2] Shiga Univ Med Sci, Dept Pharm, Shiga 5202192, Japan
[3] Univ Shiga Prefecture, Sch Human Cultures, Dept Life Style Studies, Shiga 5228533, Japan
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1999年 / 63卷 / 09期
关键词：
catechin; metal ion; DNA cleavage; antioxidant; prooxidant;
D O I：
10.1271/bbb.63.1654
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The DNA cleavage activities of (+)-catechin (C), (-)epicatechin (EC), (-)-epigallocatechin (EGC), and (-)-epigallocatechin gallate (EGCg) were examined with 16 different metal ions. Cu2+ with all the catechins facilitated DNA cleavage, while Ag+ with EGC and EC showed a strong repressive effect. The other metal ions examined showed little effect.
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页码：1654 / 1656
页数：3
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