A CASE OF EVANS' SYNDROME FOLLOWING INFLUENZA VACCINE

被引:20
作者
Shlamovitz, Gil Z. [1 ]
Johar, Sandeep [2 ]
机构
[1] Baylor Coll Med, Ben Taub Gen Hosp, Sect Emergency Med, Houston, TX 77030 USA
[2] Univ Connecticut, Hartford Hosp, Dept Emergency Med, Hartford, CT 06112 USA
关键词
Evans' syndrome; immune thrombocytopenia (ITP); autoimmune hemolytic anemia (AIHA); influenza vaccine; IMMUNE THROMBOCYTOPENIC PURPURA; ACQUIRED HEMOLYTIC-ANEMIA; AUTOIMMUNITY; DISEASE;
D O I
10.1016/j.jemermed.2012.01.060
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Background: Evans' syndrome is an uncommon condition defined by the combination (either simultaneously or sequentially) of immune thrombocytopenia purpura and autoimmune hemolytic anemia with a positive direct antiglobulin test in the absence of known underlying etiology. Objectives: We present a case of Evans' syndrome following influenza vaccination. Case Report: A 50-year-old man with no prior medical history developed Evans' syndrome 4 days after receiving influenza immunization. The patient improved following treatment with oral prednisone and intravenous immunoglobulin. Conclusion: Influenza vaccine is one of the most commonly used vaccines worldwide, with millions of people being vaccinated annually. Despite its wide use, only sparse information has been published concerning any hematological effects of this vaccine. The rarity of such effects supports the safety of using this vaccine. (c) 2013 Elsevier Inc.
引用
收藏
页码:E149 / E151
页数:3
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