Acute hepatitis and atovaquone/proguanil

被引：1

作者：

Grieshaber, M

Lämmli, J

Marcus, L

机构：

[1] Med Univ S Africa, Dept Ophthalmol, ZA-0204 Medunsa, South Africa

[2] Univ Basel Hosp, CH-4031 Basel, Switzerland

[3] Niehaus Dyson Lancet Pathologists, Pretoria, South Africa

来源：

JOURNAL OF TRAVEL MEDICINE | 2005年 / 12卷 / 05期

关键词：

D O I：

暂无

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

A 31-year-old healthy man developed acute hepatitis after receiving atovaquone (250 mg) and proguanil (100 mg) for malaria prophylaxis daily for 25 days. Although atovaquone/proguanil is generally well-tolerated, this case highlights the hepatotoxic potential with considerable morbidity and should alert physicians to this harmful side effect.

引用

页码：289 / 290

页数：2

共 6 条

[1]

Bradley D J, 2003, Commun Dis Public Health, V6, P180

[2] Atovaquone-proguanil compared with chloroquine and chloroquine-sulfadoxine-pyrimethamine for treatment of acute Plasmodium falciparum malaria in the Philippines [J].