Synthesis and Evaluation of Some New Thiazolidin-4-One Derivatives as Potential Antimicrobial Agents

被引：3

作者：

Baviskar, B. A. ^{[1
,2
]}

Khadabadi, S. S. ^{[3
]}

Deore, S. L. ^{[2
]}

机构：

[1] Govt Coll Pharm, Dept Pharmaceut Chem, Amravati 444604, Maharashtra, India

[2] Govt Coll Pharm, Dept Pharmacognosy & Phytochem, Amravati 444604, Maharashtra, India

[3] Govt Coll Pharm, Dept Pharmacognosy & Phytochem, Aurangabad 431005, Maharashtra, India

来源：

JOURNAL OF CHEMISTRY | 2013年 / 2013卷

关键词：

AZETIDINONE COMPOUNDS; SCHIFF-BASE; ANTIBACTERIAL; THIAZOLE;

D O I：

10.1155/2013/656271

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new series of N-{4-methyl-5-[4-(4-oxo-2-phenyl(1,3-thiazolidin-3-yl)]-5-sulfanyl(1,2,4-triazol-3-yl)-1,3-thiazol-2-yl]-acetamide (7a-1) was synthesized in order to determine their antimicrobial activity and feasible structure-activity relationships. The compounds were synthesized in good yield and the structures of all newly synthesized compounds were established on the basis of their IR, 1HNMR, and elemental analysis. The synthesized compounds were tested in vitro antibacterial activity against staphylococcus acureus, Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi and antifungal activity against Aspergillus niger, Candida albicans by measuring the zone of inhibition in mm.

引用

页数：6

共 50 条

[21] Synthesis and Evaluation of Ester Derivatives of 10-Hydroxycanthin-6-one as Potential Antimicrobial Agents [J].

Zhao, Fei ;

Dai, Jiang-Kun ;

Liu, Dan ;

Wang, Shi-Jun ;

Wang, Jun-Ru .

MOLECULES, 2016, 21 (03)

[22] Synthesis and biological evaluation of some 2,4,5-trisubstituted thiazole derivatives as potential antimicrobial and anticancer agents [J].

Al-Saadi, Mohammed S. ;

Faidallah, Hassan M. ;

Rostom, Sherif A. F. .

ARCHIV DER PHARMAZIE, 2008, 341 (07) :424-434

[23] Synthesis and Biological Evaluation of Some Novel Polysubstituted Pyrimidine Derivatives as Potential Antimicrobial and Anticancer Agents [J].

Rostom, Sherif A. F. ;

Ashour, Hayam M. A. ;

El Razik, Heba A. Abd .

ARCHIV DER PHARMAZIE, 2009, 342 (05) :299-310

[24] New Benzopyrrole Derivatives: Synthesis and Appraisal of Their Potential as Antimicrobial Agents [J].

Nandurkar, Deweshri ;

Menghani, Sunil ;

Danao, Kishor ;

Rokde, Vijayshri ;

Rarokar, Nilesh ;

Khedekar, Pramod ;

Mana, Supriya .

CHEMISTRY & BIODIVERSITY, 2023, 20 (07)

[25] Synthesis and Evaluation of Some Coumarin Containing Potential Antimicrobial Agents [J].

Kudale, Sayali D. ;

Deodhar, Meenakshi N. .

E-JOURNAL OF CHEMISTRY, 2012, 9 (04) :2493-2500

[26] Synthesis and evaluation of some new 5-(hetaryl)thiazoles as potential antimicrobial agents [J].

Bondock, Samir ;

Fouda, Ahmed M. .

SYNTHETIC COMMUNICATIONS, 2018, 48 (05) :561-573

[27] SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NEW TETRAHYDROPYRIMIDINE DERIVATIVES [J].

Mabkhot, Yahia N. ;

Kheder, Nabila A. ;

Farag, Ahmad M. .

HETEROCYCLES, 2011, 83 (03) :609-617

[28] SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NEW QUINALDINE DERIVATIVES [J].

Al-Abdullah, Ebtehal S. ;

Haress, Nadia G. ;

Haiba, Mogedda E. ;

Mohamed, Neama A. ;

Mahmoud, Amany Z. .

ACTA POLONIAE PHARMACEUTICA, 2017, 74 (05) :1453-1464

[29] Synthesis and Antimicrobial Evaluation of Some New Pyrimidine Derivatives [J].

Pattan, Shashikanth R. ;

Khade, A. B. ;

Khade, M. A. ;

Pattan, J. S. ;

Jadhav, S. G. ;

Dighe, N. S. ;

Nirmal, S. A. ;

Hiremath, S. V. ;

Merekar, A. N. .

INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH, 2009, 43 (03) :308-312

[30] Synthesis of some new biheterocyclic triazole derivatives and evaluation of their antimicrobial activity [J].

Bektas, Hakan ;

Demirbas, Ahmet ;

Demirbas, Neslihan ;

Karaoglu, Senguel Alpay .

TURKISH JOURNAL OF CHEMISTRY, 2010, 34 (02) :165-180

← 1 2 3 4 5 →