Post-treatment Surveillance for Stage I and II Non-small Cell Lung Cancer: Impact on Clinical Outcome

被引:3
作者
Karzijn, Renata [1 ]
Alberts, Leonie [1 ]
Kelder, Johannes C. [2 ]
Hofman, Frederik N. [3 ]
El Sharouni, Sherif Y. [4 ]
Kastelijn, Elisabeth A. [1 ]
Schramel, Franz M. N. H. [1 ]
机构
[1] St Antonius Hosp, Dept Pulmonol, POB 2500, NL-3430 EM Nieuwegein, Netherlands
[2] St Antonius Hosp, Dept Epidemiol & Stat, Nieuwegein, Netherlands
[3] St Antonius Hosp, Dept Cardiothorac Surg, Nieuwegein, Netherlands
[4] Univ Med Ctr Utrecht, Dept Radiotherapy, Utrecht, Netherlands
关键词
Early-stage non-small cell lung cancer; overall survival; progression free survival; surveillance; chest radiography; CT scan; CHEST COMPUTED-TOMOGRAPHY; FOLLOW-UP; RADIOTHERAPY; SURVIVAL; CT; RECURRENT; SURGERY; PATIENT;
D O I
10.21873/anticanres.11118
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background/Aim: Patients treated for earlystage non-small cell lung cancer (NSCLC) need post-treatment surveillance for detecting recurrence of disease. The aim of this study was to provide evidence for the appropriate follow-up. Patients and Methods: The overall survival (OS), 1- and 3-year survival and progression-free survival (PFS) were retrospectively compared between two imaging modality groups. One group received only chest radiographs (CR group) and one group received chest radiographs and at least one computed tomography scan (CT group). Results: Patients in the CR group (n=50) had no inferior OS (hazard ratio (HR)=1.427, 95% confidence interval (CI)=0.755-2.695, p=0.273) and PFS (HR=1.156, 95% CI=0.645-2.069, p=0.627) compared to patients in the CT group (n=23). Both 1-and 3-year survival were equal in the two groups (HR=5.544, 95% CI=0.530-58.031, p=0.153 and HR=1.540, 95% CI=0.752-3.154, p=0.238, respectively). Conclusion: Follow-up with a chest radiography did not result in inferior clinical outcomes compared to follow-up with a CT scan.
引用
收藏
页码:5413 / 5418
页数:6
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