A New Remote Control for Traceless meta-C-H Olefination of Phenols

被引：5
作者：
Martinez, Claudio [1 ]
Muniz, Kilian [1 ,2 ]
机构：
[1] Inst Chem Res Catalonia ICIQ, Tarragona 43007, Spain
[2] Catalan Inst Res & Adv Studies ICREA, Barcelona 08010, Spain
来源：
CHEMCATCHEM | 2013年 / 5卷 / 12期
关键词：
CH functionalization; Heck; oxidation; palladium; phenols; DIRECTING GROUP; FUNCTIONALIZATION; ALKENYLATION; ARYLATION; SILANOL;
D O I：
10.1002/cctc.201300538
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Ghosting the directing group: A clever design of a nitrile based catalyst directing group, serves as tool in the palladium-catalyzed meta-olefination of phenol derivatives. This group can be removed tracelessly, thus providing a convenient route to meta-substitution of phenols, a transformation that cannot be conducted by classic aromatic substitution chemistry. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：3502 / 3503
页数：2
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