Study on compression behavior of porous magnesium used as bone tissue engineering scaffolds

被引:44
作者
Tan, Lili [1 ]
Gong, Mingming [1 ,2 ]
Zheng, Feng [1 ]
Zhang, Bingchun [1 ]
Yang, Ke [1 ]
机构
[1] Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China
[2] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
关键词
UNIDIRECTIONAL SOLIDIFICATION; PORE-SIZE; HYDROXYAPATITE; REPLACEMENT; CARTILAGE; POROSITY; MATRIX;
D O I
10.1088/1748-6041/4/1/015016
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
In this work, porous magnesium (Mg) with a three-dimensional open-cellular structure, potentially employed as bone tissue engineering scaffolds, was fabricated by the mechanical perforation method. The influences of porosity, pore size and pore arrangement on compressive behavior and the anisotropy of new porous Mg were analyzed theoretically using orthogonal arrays and the finite element method (FEM). The results showed that the parameters of porosity, pore size and pore arrangement had different effects on the compressive properties. The compressive strength could be improved by optimizing these parameters. The anisotropy of porous Mg was also verified in this study. The theoretical results showed good agreement with the experimental ones before the strain reaches 0.038.
引用
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页数:7
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