Facile synthesis of N-protected γ and δ-amino-β-keto-esters

被引：0

作者：

Li, BQ ^{[1
]}

Franck, RW ^{[1
]}

机构：

[1] CUNY Hunter Coll, Dept Chem, New York, NY 10021 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1999年 / 9卷 / 17期

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D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The C-acylation of Meldrum's acid by protected amino acids, using isopropenyl chloroformate (IPCF) as the condensing agent, is described. The process is used to synthesize gamma and delta-amino-beta-keto-esters. (C) 1999 Elsevier Science Ltd. All rights reserved.

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页码：2629 / 2634

页数：6

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