Reaction-diffusion systems for the macroscopic bidomain model of the cardiac electric field

被引:87
作者
Veneroni, Marco [1 ]
机构
[1] Eindhoven Univ Technol, Dept Math & Comp Sci, NL-5600 MB Eindhoven, Netherlands
关键词
Reaction-diffusion equations; Bidomain model; Degenerate evolution equations; 3-D MODELS; TISSUE; EXCITATION; ANISOTROPY; EVOLUTION; HOMOGENIZATION; REPOLARIZATION; SIMULATIONS; PROPAGATION; ACTIVATION;
D O I
10.1016/j.nonrwa.2007.11.008
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
The paper deals with a mathematical model for the electric activity of the heart at the macroscopic level. The membrane model used to describe the ionic currents is a generalization of the phase-I Luo-Rudy, a model widely used in 2-D and 3-D simulations of the propagation of the action potential. From the mathematical viewpoint the model is made up of a degenerate parabolic reaction diffusion system coupled with an ODE system. We derive existence, uniqueness and some regularity results. (C) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:849 / 868
页数:20
相关论文
共 57 条
[1]   A simple two-variable model of cardiac excitation [J].
Aliev, RR ;
Panfilov, AV .
CHAOS SOLITONS & FRACTALS, 1996, 7 (03) :293-301
[2]  
Amann Herbert, 1990, Differential Integral Equations, V3, P13, DOI 10.57262/die/1371586185
[3]   On a hierarchy of models for electrical conduction in biological tissues [J].
Amar, M ;
Andreucci, D ;
Bisegna, P ;
Gianni, R .
MATHEMATICAL METHODS IN THE APPLIED SCIENCES, 2006, 29 (07) :767-787
[4]   Existence and uniqueness for an elliptic problem with evolution arising in electrodynamics [J].
Amar, M ;
Andreucci, D ;
Bisegna, P ;
Gianni, R .
NONLINEAR ANALYSIS-REAL WORLD APPLICATIONS, 2005, 6 (02) :367-380
[5]   Evolution and memory effects in the homogenization limit for electrical conduction in biological tissues [J].
Amar, M ;
Andreucci, D ;
Gianni, R .
MATHEMATICAL MODELS & METHODS IN APPLIED SCIENCES, 2004, 14 (09) :1261-1295
[6]   An elliptic equation with history [J].
Amar, M ;
Andreucci, D ;
Bisegna, P ;
Gianni, R .
COMPTES RENDUS MATHEMATIQUE, 2004, 338 (08) :595-598
[7]  
[Anonymous], 1967, GRUNDLEHREN MATH WIS
[8]   RECONSTRUCTION OF ACTION POTENTIAL OF VENTRICULAR MYOCARDIAL FIBERS [J].
BEELER, GW ;
REUTER, H .
JOURNAL OF PHYSIOLOGY-LONDON, 1977, 268 (01) :177-210
[9]   Existence and uniqueness of the solution for the bidomain model used in cardiac electrophysiology [J].
Bourgault, Yves ;
Coudiere, Yves ;
Pierre, Charles .
NONLINEAR ANALYSIS-REAL WORLD APPLICATIONS, 2009, 10 (01) :458-482
[10]  
CANNARSA P, 1986, B UNIONE MAT ITAL, V5B, P165