NS1738, a Positive Allosteric Modulator of Alpha7 Nicotinic Receptors, as Adjunctive Treatment in Schizophrenia. An Experimental Study

被引：0
|
作者：
Marcus, Monica M. [1 ]
Konradsson-Geuken, Asa [1 ]
Feltmann, Kristin [1 ]
Ivanov, Vladimir [1 ]
Schilstrom, Bjorn [1 ]
Jardemark, Kent [1 ]
Svensson, Torgny H. [1 ]
机构：
[1] Karolinska Inst, Stockholm, Sweden
来源：
NEUROPSYCHOPHARMACOLOGY | 2013年 / 38卷
关键词：
alpha7 nicotinic receptor; PAM; antipsychotic drug schizophrenia; cognition; dopamine; NMDA; prefrontal cortex;
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
W201
引用
收藏
页码：S570 / S571
页数：2
相关论文
共 50 条
  • [1] NS1738, a positive allosteric modulator of Alpha7 nicotinic receptors, as adjunctive treatment in schizophrenia. An experimental study
    Jardemark, K.
    Konradsson-Geuken, A.
    Feltmann, K.
    Ivanov, V.
    Schilstrom, B.
    Marcus, M. M.
    Svensson, T.
    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2014, 17 : 107 - 107
  • [2] Alpha7 nicotinic acetylcholine receptor agonists and PAMs as adjunctive treatment in schizophrenia. An experimental study
    Marcus, Monica M.
    Bjorkholm, Carl
    Malmerfelt, Anna
    Moller, Annie
    Pahlsson, Ninni
    Konradsson-Geuken, Asa
    Feltmann, Kristin
    Jardemark, Kent
    Schilstrom, Bjorn
    Svensson, Torgny H.
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2016, 26 (09) : 1401 - 1411
  • [3] Alpha7 Nicotinic Receptors as Therapeutic Targets in Schizophrenia
    Tregellas, Jason R.
    Wylie, Korey P.
    NICOTINE & TOBACCO RESEARCH, 2019, 21 (03) : 349 - 356
  • [4] Alpha7 neuronal nicotinic receptors as a drug target in schizophrenia
    Wallace, Tanya L.
    Bertrand, Daniel
    EXPERT OPINION ON THERAPEUTIC TARGETS, 2013, 17 (02) : 139 - 155
  • [5] Stereochemical requirements within the tetrahydroquinoline scaffold for the positive allosteric modulation at alpha7 nicotinic acetylcholine receptors
    Kulkarni, Abhijit R.
    Deschamps, Jeffrey
    Papke, Roger L.
    Thakur, Ganesh A.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 246
  • [6] Theoretical study of the binding profile of an allosteric modulator NS-1738 with a chimera structure of the α7 nicotinic acetylcholine receptor
    Kuang, Guanglin
    Wang, Xu
    Halldin, Christer
    Nordberg, Agneta
    Langstrom, Bengt
    Agren, Hans
    Tu, Yaoquan
    PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2016, 18 (40) : 28003 - 28009
  • [7] Development of an allosteric modulator functional assay and characterization of the nicotinic acetylcholine receptor alpha7 (nAChR α7) positive modulator PNU-120596
    Sahdeo, Sunil
    Misner, Dinah
    Santarelli, Luca
    Milla, Marcos
    Button, Donald
    FASEB JOURNAL, 2007, 21 (06): : A789 - A789
  • [8] Alpha7 nicotinic receptors as potential theranostic targets for experimental stroke
    Garbizu, Maider
    Aguado, Laura
    Martin, Abraham
    NEURAL REGENERATION RESEARCH, 2024, 19 (05) : 939 - 940
  • [9] Alpha7 nicotinic receptors as potential theranostic targets for experimental stroke
    Maider Garbizu
    Laura Aguado
    Abraham Martín
    Neural Regeneration Research, 2024, 19 (05) : 939 - 940
  • [10] Positive Allosteric Modulators of alpha7 Nicotinic Acetylcholine Receptor for the Treatment of Several Central Nervous System Diseases
    Abdel-Magid, Ahmed F.
    ACS MEDICINAL CHEMISTRY LETTERS, 2023, 15 (01): : 6 - 8
12345