Three-year Review of Bacteriological Profile and Antibiogram of Burn Wound Isolates in Van, Turkey

被引:55
作者
Bayram, Yasemin [1 ]
Parlak, Mehmet [1 ]
Aypak, Cenk [2 ]
Bayram, Irfan [3 ]
机构
[1] Van Training & Res Hosp, Microbiol Lab, Van, Turkey
[2] Van Gevas State Hosp, Dept Family Med, Van, Turkey
[3] Yuzuncu Yil Univ, Fac Med, Dept Pathol, Van, Turkey
关键词
antibiotic; burns; resistance; wounds; INTENSIVE-CARE-UNIT; GRAM-NEGATIVE BACILLI; NOSOCOMIAL INFECTIONS; ACINETOBACTER-BAUMANNII; EPIDEMIOLOGY; EXPERIENCE; AUTOPSY; INJURY; INDIA; SIZE;
D O I
10.7150/ijms.4723
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The risk of infection in burns is well-known. In recent decades, the antimicrobial resistance of bacteria isolated from burn patients has increased. For this reason, a retrospective study was conducted at Van Training and Research Hospital to analyze the bacterial isolates from the wounds of patients admitted to the Burn Unit and to determine the susceptibility patterns of the commonly cultured organisms over a 3-year period, January 2009 to December 2011. A total of 250 microorganisms were isolated from burn wounds of 179 patients. Our results revealed that the most frequent isolate was Acinetobacter baumannii (23.6%), Pseudomonas aeruginosa (12%), Staphylococcus aureus (11.2%), Escherichia coli (10%) respectively. Multidrug-resistance has emerged as an important concern in our burn unit. Tigecycline, and colistin were found to be the most active drugs against Acinetobacter baumannii. Carbapenems and amikacin, were found to be the most active drugs against other gram negative bacteria. Vancomycin and linezolid were active against gram positive bacteria. Aggressive infection control measures should be applied to limit the emergence and spread of multidrug-resistant pathogens.
引用
收藏
页码:19 / 23
页数:5
相关论文
共 40 条
[1]   A prospective double-blinded comparative analysis of framycetin and silver sulphadiazine as topical agents for burns: A pilot study [J].
Ahuja, Rajeev B. ;
Gupta, Amit ;
Gur, Renu .
BURNS, 2009, 35 (05) :672-676
[2]   Relationships between burn size, immuno suppression, and macrophage hyperactivity in a murine model of thermal injury [J].
Alexander, M ;
Chaudry, IH ;
Schwacha, MG .
CELLULAR IMMUNOLOGY, 2002, 220 (01) :63-69
[3]   A prospective study of infections in burn patients [J].
Appelgren, P ;
Björnhagen, V ;
Bragderyd, K ;
Jonsson, CE ;
Ransjö, U .
BURNS, 2002, 28 (01) :39-46
[4]   Prophylactic antibiotics for burns patients: systematic review and meta-analysis [J].
Avni, Tomer ;
Levcovich, Ariela ;
Ad-El, Dean D. ;
Leibovici, Leonard ;
Paul, Mical .
BMJ-BRITISH MEDICAL JOURNAL, 2010, 340 :517
[5]   Five-year review of infections in a burn intensive care unit:: High incidence of Acinetobacter baumannii in a tropical climate [J].
Chim, Harvey ;
Tan, Ban Hock ;
Song, Colin .
BURNS, 2007, 33 (08) :1008-1014
[6]   Burn wound infections [J].
Church, D ;
Elsayed, S ;
Reid, O ;
Winston, B ;
Lindsay, R .
CLINICAL MICROBIOLOGY REVIEWS, 2006, 19 (02) :403-+
[7]   Nosocomial infections in a Brazilian Burn Unit [J].
de Macedo, Jefferson Lessa Soares ;
Santos, Joao Barberino .
BURNS, 2006, 32 (04) :477-481
[8]   Bacterial and fungal colonization of burn wounds [J].
de Macedo, JLS ;
Santos, JB .
MEMORIAS DO INSTITUTO OSWALDO CRUZ, 2005, 100 (05) :535-539
[9]   The epidemiology and control of Acinetobacter baumannii in health care facilities [J].
Fournier, PE ;
Richet, H .
CLINICAL INFECTIOUS DISEASES, 2006, 42 (05) :692-699
[10]   Clinical and economic impact of common multidrug-resistant gram-negative bacilli [J].
Giske, Christian G. ;
Monnet, Dominique L. ;
Cars, Otto ;
Carmeli, Yehuda .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2008, 52 (03) :813-821